相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Hyperoxic Acute Lung Injury
Richard H. Kallet et al.
RESPIRATORY CARE (2013)
Regulation of the cell cycle via mitochondrial gene expression and energy metabolism in HeLa cells
Wei Xiong et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2012)
A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia-reperfusion
Yi-Shuai Zhang et al.
BASIC RESEARCH IN CARDIOLOGY (2012)
Metabolic adaptation to chronic hypoxia in cardiac mitochondria
Lisa C. Heather et al.
BASIC RESEARCH IN CARDIOLOGY (2012)
Involvement of the MAPK and P13K pathways in chitinase 3-like 1-regulated hyperoxia-induced airway epithelial cell death
Mi Na Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Hypoxia-inducible Factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells
Jin-e Ao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition off superoxide production
Sun Ah Ham et al.
BIOCHEMICAL JOURNAL (2012)
p53 Ser15 phosphorylation disrupts the p53-RPA70 complex and induces RPA70-mediated DNA repair in hypoxia
Esha Madan et al.
BIOCHEMICAL JOURNAL (2012)
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells
Chiemi Nishida et al.
BLOOD (2012)
TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex
E. Madan et al.
BRITISH JOURNAL OF CANCER (2012)
Evidence for cell cycle suppression and microRNA regulation of cyclin D1 during anoxia exposure in turtles
Kyle K. Biggar et al.
CELL CYCLE (2012)
FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression
E. C. Ferber et al.
CELL DEATH AND DIFFERENTIATION (2012)
Chromatin as an oxygen sensor and active player in the hypoxia response
Andrew Melvin et al.
CELLULAR SIGNALLING (2012)
Chaperoning of Mutant p53 Protein by Wild-type p53 Protein Causes Hypoxic Tumor Regression
Rajan Gogna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability
Ramya Kumareswaran et al.
JOURNAL OF CELL SCIENCE (2012)
C-Terminal Heat Shock Protein 90 Inhibitor Decreases Hyperglycemia-induced Oxidative Stress and Improves Mitochondrial Bioenergetics in Sensory Neurons
Liang Zhang et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Inhibition of ROS-activated ERK1/2 pathway contributes to the protection of H2S against chemical hypoxia-induced injury in H9c2 cells
Xiao-Bian Dong et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2012)
Policing Cells under Stress: Noncoding RNAs Capture Proteins in Nucleolar Detention Centers
Kannanganattu V. Prasanth
MOLECULAR CELL (2012)
Immobilization of Proteins in the Nucleolus by Ribosomal Intergenic Spacer Noncoding RNA
Timothy E. Audas et al.
MOLECULAR CELL (2012)
mTOR activates hypoxia-inducible factor-1α and inhibits neuronal apoptosis in the developing rat brain during the early phase after hypoxia-ischemia
Hongju Chen et al.
NEUROSCIENCE LETTERS (2012)
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
U. Weyemi et al.
ONCOGENE (2012)
Parallel pathways in RAF-induced senescence and conditions for its reversion
M. Jeanblanc et al.
ONCOGENE (2012)
Activation of CD40 with Platelet Derived CD154 Promotes Reactive Oxygen Species Dependent Death of Human Hepatocytes during Hypoxia and Reoxygenation
Ricky H. Bhogal et al.
PLOS ONE (2012)
UCP2 Inhibits ROS-Mediated Apoptosis in A549 under Hypoxic Conditions
Sanming Deng et al.
PLOS ONE (2012)
Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling
Hong Wei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Transduction of Neural Precursor Cells with TAT-Heat Shock Protein 70 Chaperone: Therapeutic Potential Against Ischemic Stroke after Intrastriatal and Systemic Transplantation
Thorsten R. Doeppner et al.
STEM CELLS (2012)
Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells
Ji Hye Kim et al.
STEM CELLS AND DEVELOPMENT (2012)
Effect of Small Interfering RNA Targeting Hypoxia-inducible Factor-1α on Radiosensitivity of PC3 Cell Line
Yuhua Huang et al.
UROLOGY (2012)
Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells
R. Elanchezhian et al.
CELL DEATH & DISEASE (2012)
Re-oxygenation causes hypoxic tumor regression through restoration of p53 wild-type conformation and post-translational modifications
R. Gogna et al.
CELL DEATH & DISEASE (2012)
Targeting the p53 Pathway to Protect the Neonatal Ischemic Brain
Cora H. Nijboer et al.
ANNALS OF NEUROLOGY (2011)
Mitochondrial superoxide anion radicals mediate induction of apoptosis in cardiac myoblasts exposed to chronic hypoxia
Rajitha T. Kolamunne et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Lipopolysaccharide induces apoptotic insults to human alveolar epithelial A549 cells through reactive oxygen species-mediated activation of an intrinsic mitochondrion-dependent pathway
Chi-Yuan Chuang et al.
ARCHIVES OF TOXICOLOGY (2011)
Overexpression of the human ubiquitin E3 ligase CUL4A alleviates hypoxia-reoxygenation injury in pheochromocytoma (PC12) cells
Can Tan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia
Philippe Pasdois et al.
BIOCHEMICAL JOURNAL (2011)
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
Gregg L. Semenza
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
S. Y. Nam et al.
BRITISH JOURNAL OF CANCER (2011)
Introduction of hypoxia-targeting p53 fusion protein for the selective therapy of non-small cell lung cancer
Yu Zhao et al.
CANCER BIOLOGY & THERAPY (2011)
Knockdown of β-Catenin Through shRNA Cause a Reversal of EMT and Metastatic Phenotypes Induced by HIF-1α
Jia-Hui Zhao et al.
CANCER INVESTIGATION (2011)
Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1
Patrick A. Mayes et al.
CANCER RESEARCH (2011)
HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia
Pablo A. Robador et al.
CARDIOVASCULAR RESEARCH (2011)
HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs
Carolyn Culver et al.
CELL CYCLE (2011)
Hypoxia Are stem cells in it for the long run?
Philip Davy et al.
CELL CYCLE (2011)
The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA
Jennifer S. Gewandter et al.
CELL CYCLE (2011)
Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2
Anjali Nandal et al.
CELL METABOLISM (2011)
Bcl-XL Is the primary mediator of p21 protection against hyperoxia-induced cell death
Yu-Chieh M. Wu et al.
EXPERIMENTAL LUNG RESEARCH (2011)
Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1α in adipocytes
Yoshitaka Kihira et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Synergistic Induction of Galectin-1 by CCAAT/Enhancer Binding Protein α and Hypoxia-inducible Factor 1α and Its Role in Differentiation of Acute Myeloid Leukemic Cells
Xu-Yun Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Superoxide Flashes EARLY MITOCHONDRIAL SIGNALS FOR OXIDATIVE STRESS-INDUCED APOPTOSIS
Qi Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions
Jae Young Choi et al.
JOURNAL OF BREAST CANCER (2011)
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia
Fanny Bouquet et al.
JOURNAL OF CELL SCIENCE (2011)
Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL
Mingqing Li et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Thrombin Induces Expression of Twist and Cell Motility Via the Hypoxia-Inducible Factor-1α Translational Pathway in Colorectal Cancer Cells
Li-Hsun Chang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-kappa B signaling
Ying Qu et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes
Xue-Yuan Bai et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase
Xiao-Li Zhang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter
Yuhong Lu et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Hypoxia-Inducible Factor 1 Is Activated by Dysregulated Cyclin E during Mammary Epithelial Morphogenesis
Tanushri Sengupta et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
Ulrike Bruning et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Mouse Snail Is a Target Gene for HIF
Daochun Luo et al.
MOLECULAR CANCER RESEARCH (2011)
Transcriptional Upregulation of MT2-MMP in Response to Hypoxia Is Promoted by HIF-1α in Cancer Cells
Shikai Zhu et al.
MOLECULAR CARCINOGENESIS (2011)
MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
Maimon E. Hubbi et al.
MOLECULAR CELL (2011)
Age Related Changes in NAD plus Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats (Publication with Expression of Concern. See vol. 17, 2022)
Nady Braidy et al.
PLOS ONE (2011)
Hyperoxia Impairs Alveolar Formation and Induces Senescence Through Decreased Histone Deacetylase Activity and Up-Regulation of p21 hi Neonatal Mouse Lung
Vedang A. Londhe et al.
PEDIATRIC RESEARCH (2011)
Reciprocal influence of the p53 and the hypoxic pathways
A. Sermeus et al.
CELL DEATH & DISEASE (2011)
The impact of acetylation and deacetylation on the p53 pathway
Christopher L. Brooks et al.
PROTEIN & CELL (2011)
p53 target Siva regulates apoptosis in ischemic kidneys
Kurinji Singaravelu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2
Marcelo G. Binker et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species
Andreas Daiber
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)
Hyperthermic preconditioning protects astrocytes from ischemia/reperfusion injury by up-regulation of HIF-1 alpha expression and binding activity
Fang Du et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Mild hyperoxia limits hTR levels, telomerase activity, and telomere length maintenance in hTERT-transduced bone marrow endothelial cells
Christine E. Napier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)
Reactive Oxygen Species Mediate Mitogenic Growth Factor Signaling Pathways in Human Leiomyoma Smooth Muscle Cells
Fernando S. Mesquita et al.
BIOLOGY OF REPRODUCTION (2010)
Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells
Paul S. Hole et al.
BLOOD (2010)
Metastasis: cancer cell's escape from oxidative stress
Giovambattista Pani et al.
CANCER AND METASTASIS REVIEWS (2010)
JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70
Dongyun Zhang et al.
CANCER RESEARCH (2010)
Suppression of Cyclin D1 by Hypoxia-Inducible Factor-1 via Direct Mechanism Inhibits the Proliferation and 5-Fluorouracil-Induced Apoptosis of A549 Cells
Wen Wen et al.
CANCER RESEARCH (2010)
MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis
Shih-Ting Cha et al.
CANCER RESEARCH (2010)
Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease
Susana Cadenas et al.
CARDIOVASCULAR RESEARCH (2010)
Promotion of CHIP-Mediated p53 Degradation Protects the Heart From Ischemic Injury
Atsuhiko T. Naito et al.
CIRCULATION RESEARCH (2010)
The phosphatidylinositol 3-kinase-Akt pathway protects cardiomyocytes from ischaemic and hypoxic apoptosis via mitochondrial function
Hua-Pei Song et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
Hsp20 Protects Neuroblastoma Cells from Ischemia/Reperfusion Injury by Inhibition of Apoptosis via a Mechanism that Involves the Mitochondrial Pathways
Liuwang Zeng et al.
CURRENT NEUROVASCULAR RESEARCH (2010)
N-acetylcysteine protects alveolar epithelial cells from hydrogen peroxide-induced apoptosis through scavenging reactive oxygen species and suppressing c-Jun N-terminal kinase
Yue-qiang Fu et al.
EXPERIMENTAL LUNG RESEARCH (2010)
Reactive oxygen species produced by the knockdown of manganese-superoxide dismutase up-regulate hypoxia-inducible factor-1α expression in oral squamous cell carcinoma cells
Eri Sasabe et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia INSIGHTS INTO CELLULAR TRANSFORMATION PROCESSES MEDIATED BY HIF-1
Ruth Schietke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Complex Regulation of the Transactivation Function of Hypoxia-inducible Factor-1α by Direct Interaction with Two Distinct Domains of the CREB-binding Protein/p300
Jorge L. Ruas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Identification of a Survival-independent Metastasis-enhancing Role of Hypoxia-inducible Factor-1α with a Hypoxia-tolerant Tumor Cell Line
Florian Schelter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Roles of GRP78 in Physiology and Cancer
Lu-Hua Zhang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Hydroxylase Inhibition Abrogates TNF-α-Induced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1-Dependent Repression of FADD
Pieter Hindryckx et al.
JOURNAL OF IMMUNOLOGY (2010)
SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
Barrie Peck et al.
MOLECULAR CANCER THERAPEUTICS (2010)
O2 regulates stem cells through Wnt/β-catenin signalling
Jolly Mazumdar et al.
NATURE CELL BIOLOGY (2010)
Mechanism of Post-Translational Modification by Tyrosine Phosphorylation of Apoptotic Proteins During Hypoxia in the Cerebral Cortex of Newborn Piglets
Maria Delivoria-Papadopoulos et al.
NEUROCHEMICAL RESEARCH (2010)
The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway
A. Salmeen et al.
ONCOGENE (2010)
Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
S. Eliasz et al.
ONCOGENE (2010)
被撤回的出版物: Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90 (Retracted article. See vol. 17, 2022)
Daniela Trisciuoglio et al.
PLOS ONE (2010)
RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1α as critical for telomerase function in murine embryonic stem cells
Matthew Coussens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
Munekazu Yamakuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation
Narasaiah Kolliputi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis
Dong Xu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
The Unfolded Protein Response in Health and Disease
Richard C. Austin
ANTIOXIDANTS & REDOX SIGNALING (2009)
Alternative Splicing of Cyr61 Is Regulated by Hypoxia and Significantly Changed in Breast Cancer
Marc Hirschfeld et al.
CANCER RESEARCH (2009)
Modes of p53 Regulation
Jan-Philipp Kruse et al.
CELL (2009)
HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia
Thomas Hackenbeck et al.
CELL CYCLE (2009)
Perspectives in Cell Cycle Regulation: Lessons from an Anoxic Vertebrate
Kyle K. Biggar et al.
CURRENT GENOMICS (2009)
Modifications of p53: competing for the lysines
Stephanie Carter et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS
Tatyana A. Klimova et al.
FASEB JOURNAL (2009)
Hyperoxia augments ER-stress-induced cell death independent of BiP loss
Jennifer S. Gewandter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
p21(Cip1) protects against oxidative stress by suppressing ER-dependent activation of mitochondrial death pathways
Peter F. Vitiello et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Routine use of oxygen in the treatment of myocardial infarction: systematic review
M. Wijesinghe et al.
HEART (2009)
SWI/SNF Regulates the Cellular Response to Hypoxia
Niall S. Kenneth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Activation of Cu,Zn-Superoxide Dismutase in the Absence of Oxygen and the Copper Chaperone CCS
Jeffry M. Leitch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Kruppel-like Factor 2 Inhibits Hypoxia-inducible Factor 1α Expression and Function in the Endothelium
Daiji Kawanami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Ischemia Activates the ATF6 Branch of the Endoplasmic Reticulum Stress Response
Shirin Doroudgar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes
Cong Cao et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence
Olga Moiseeva et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Inhibition of HIF-Ialpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis
Lavinia Nardinocchi et al.
MOLECULAR CANCER (2009)
Effect of Hyperoxia on Serine Phosphorylation of Apoptotic Proteins in Mitochondrial Membranes of the Cerebral Cortex of Newborn Piglets
Nadege A. Brutus et al.
NEUROCHEMICAL RESEARCH (2009)
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
Yair Benita et al.
NUCLEIC ACIDS RESEARCH (2009)
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells
S. H. Lee et al.
ONCOGENE (2009)
Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model
Ingrid Moen et al.
PLOS ONE (2009)
COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1α via HSP90/70
Bart van de Sluis et al.
PLOS ONE (2009)
Heat Shock Protein 27 Protects Lung Epithelial Cells From Hyperoxia-Induced Apoptotic Cell Death
Lei Shao et al.
PEDIATRIC RESEARCH (2009)
Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cells
Louise Ostergaard et al.
PROTEOMICS (2009)
Effect of an Inducer of BiP, a Molecular Chaperone, on Endoplasmic Reticulum (ER) Stress-Induced Retinal Cell Death
Yuta Inokuchi et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
PERP, a p53 proapoptotic target, mediates apoptotic cell death in renal ischemia
Kurinji Singaravelu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation
Amit Kulkarni et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species
Wen-Sheng Wu et al.
CANCER AND METASTASIS REVIEWS (2008)
VHL inactivation: A new road to senescence
William Y. Kim et al.
CANCER CELL (2008)
Activation of protein kinase G increases the expression of p21CIP1, p27KIP1, and Histidine triad protein 1 through Sp1
Bo Cen et al.
CANCER RESEARCH (2008)
Identification of hypoxia-inducible factor-1α as a novel target for miR-17-92 microRNA cluster
Ayumu Taguchi et al.
CANCER RESEARCH (2008)
Superoxide flashes in single mitochondria
Wang Wang et al.
CELL (2008)
A microRNA component of the hypoxic response
R. Kulshreshtha et al.
CELL DEATH AND DIFFERENTIATION (2008)
Comparison of the effects of 40% oxygen and two atmospheric absolute air pressure conditions on stress-induced premature senescence of normal human diploid fibroblasts
Sangnam Oh et al.
CELL STRESS & CHAPERONES (2008)
Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging
Stefania Briganti et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Proinflammatory cytokine-induced cellular senescence of biliary epithelial cells is mediated via oxidative stress and activation of ATM pathway: A culture study
Motoko Sasaki et al.
FREE RADICAL RESEARCH (2008)
Instability of Superoxide Dismutase 1 of Drosophila in Mutants Deficient for Its Cognate Copper Chaperone
Kim Kirby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Hypoxia/reoxygenation: A dynamic regulator of lysyl oxidase-facilitated breast cancer migration
Lynne-Marie Postovit et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Bax Shuttling After Neonatal Hypoxia-Ischemia: Hyperoxia Effects
Martin B. Gill et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
Arthur P. Young et al.
NATURE CELL BIOLOGY (2008)
Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence
C. Leikam et al.
ONCOGENE (2008)
PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
G. Xenaki et al.
ONCOGENE (2008)
Telomere dysfunction and tumour suppression: the senescence connection
Yibin Deng et al.
NATURE REVIEWS CANCER (2008)
Hypoxia, DNA repair and genetic instability
Robert G. Bristow et al.
NATURE REVIEWS CANCER (2008)
Reactive oxygen-mediated damage to a human DNA replication and repair protein
Beatriz Montaner et al.
EMBO REPORTS (2007)
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
Yoon-Young Jang et al.
BLOOD (2007)
Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells
Elke H. Heiss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Redox control of G1/S cell cycle regulators during nitric oxide-mediated cell cycle arrest
Qi Lu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Mechanistic studies of MDM2-mediated ubiquitination in p53 regulation
Christopher L. Brooks et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia
Eric L. Bell et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1
Marc U. Baumann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Effect of hyperoxia on cortical neuronal nuclear function and programmed cell death mechanisms
Eddie Chang et al.
NEUROCHEMICAL RESEARCH (2007)
Hypoxia-inducible factor-1α, a key factor in the keratinocyte response to UVB exposure
Hamid Reza Rezvani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2
S-J Lee et al.
CELL DEATH AND DIFFERENTIATION (2007)
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
Ryo Fukuda et al.
CELL (2007)
HIF-2α promotes hypoxic cell proliferation by enhancing c-Myc transcriptional activity
John D. Gordan et al.
CANCER CELL (2007)
Induction of DNA hypomethylation by tumor hypoxia
Siranoush Shahrzad et al.
EPIGENETICS (2007)
Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway
Isabelle Metrailler-Ruchonnet et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
A microRNA signature of hypoxia
Ritu Kulshreshtha et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
RACK1 competes with HSP90 for binding to HIF-1α and is required for O2-independent and HSP90 inhibitor-induced degradation of HIF-1α
Ye V. Liu et al.
MOLECULAR CELL (2007)
Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation
Xue Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation
Ying Cai et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Thioredoxin-1 protects against hyperoxia-induced apoptosis in cells of the alveolar walls
Tadaaki Yamada et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2007)
The signaling mechanism of ROS in tumor progression
Wen-Sheng Wu
CANCER AND METASTASIS REVIEWS (2006)
Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics
William A. Holtz et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Gene expression profile of human airway epithelium induced by hyperoxia in vivo
Arnaud Chambellan et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)
Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia
Ahmad W. Husari et al.
RESPIRATORY RESEARCH (2006)
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
Karim Bensaad et al.
CELL (2006)
Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia
Abderrahmane Kaidi et al.
CANCER RESEARCH (2006)
p53 regulates mitochondrial respiration
Satoaki Matoba et al.
SCIENCE (2006)
Regulation of late G1/S phase transition and APCCdh1 by reactive oxygen species
Courtney G. Havens et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
NADPH oxidases in cardiovascular health and disease
Alison C. Cave et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism
MS Ullah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou et al.
CELL METABOLISM (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Effect of reoxygenation on the hypoxia-induced up-regulation of serine protease inhibitor PAI-1 in head and neck cancer cells
Lisa D. Sprague et al.
ONCOLOGY (2006)
Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
P Jezek et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Tumor necrosis factor α (TNFα) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFα
X Xue et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury
R Seth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
A Rivera et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
M Giorgio et al.
CELL (2005)
Preventing re-replication of chromosomal DNA
JJ Blow et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
The ATM/p53/p21 pathway influences cell fate decision between apoptosis and senescence in reoxygenated hematopoietic progenitor cells
XL Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells
ZH Liu et al.
CANCER RESEARCH (2005)
ERp57 is a multifunctional thiol-disulfide oxidoreductase
EM Frickel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1α from pVHL-independent degradation
J Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Redox regulation of DNA binding activity of DREF (DNA replication-related element binding factor) in Drosophila
TY Choi et al.
BIOCHEMICAL JOURNAL (2004)
O2-regulated gene expression:: transcriptional control of cardiorespiratory physiology by HIF-1
GL Semenza
JOURNAL OF APPLIED PHYSIOLOGY (2004)
The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia
CE Helt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells
LJ Buccellato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hyperoxia, reactive oxygen species, and hyperventilation: oxygen sensitivity of brain stem neurons
JB Dean et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Induction of ID2 expression by hypoxia-inducible factor-1 -: A role in dedifferentiation of hypoxic neuroblastoma cells
T Löfstedt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation
EM Hammond et al.
DNA REPAIR (2004)
Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines
S Kokura et al.
CANCER LETTERS (2004)
ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brain
H Kitano et al.
BRAIN RESEARCH (2004)
Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites
KC Das et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene
F Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1 alpha stabilization
DM Katschinski et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2004)
Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Reactive oxygen species induce RNA damage in human atherosclerosis
W Martinet et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2004)
Analyzing changes of chromatin-bound replication proteins occurring in response to and after release from a hypoxic block of replicon initiation in T24 cells
M van Betteraey-Nikoleit et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Hsp90 inhibition accelerates cell lysis -: Anti-Hsp90 ribozyme reveals a complex mechanism of Hsp90 inhibitors involving both superoxide- and Hsp90-dependent events
AS Sreedhar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells
YH Ling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite
XL Gu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
HIF-1 in cell cycle regulation, apoptosis, and tumor progression
N Goda et al.
ANTIOXIDANTS & REDOX SIGNALING (2003)
Identification of a human homologue of the DREF transcription factor with a potential role in regulation of the histone H1 gene
N Ohshima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
CL Brooks et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
Hypoxia-inducible factor 1 alpha is essential for cell cycle arrest during hypoxia
N Goda et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Influence of induced reactive oxygen species in p53-mediated cell fate decisions
S Macip et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Structure, mechanism and regulation of peroxiredoxins
ZA Wood et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Ablation of the heat shock factor-1 increases susceptibility to hyperoxia-mediated cellular injury
V Malhotra et al.
EXPERIMENTAL LUNG RESEARCH (2002)
Regulation of gene expression by oxygen:: NF-κB and HIF-1, two extremes
C Michiels et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Live or let die: The cell's response to p53
KH Vousden et al.
NATURE REVIEWS CANCER (2002)
Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death
M Miyazaki et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration
C Grimm et al.
NATURE MEDICINE (2002)
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis
M Trinei et al.
ONCOGENE (2002)
Hyperoxia-induced apoptosis does not require mitochondrial reactive oxygen species and is regulated by Bcl-2 proteins
GRS Budinger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Re-oxygenation of hypoxic simian virus 40 (SV40)-infected CV1 cells causes distinct changes of SV40 minichromosome-associated replication proteins
HJ Riedinger et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans
PA Padilla et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Oncogenic ras and p53 cooperate to induce cellular senescence
G Ferbeyre et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene -: Its possible role in the Warburg effect
A Minchenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Hypoxia - A key regulatory factor in tumour growth
AL Harris
NATURE REVIEWS CANCER (2002)
Oxygen-dependent regulation of in vivo replication of simian virus 40 DNA is modulated by glucose
HJ Riedinger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
p53-dependent induction of p21Cip1/WAF1/Sdi1 protects against oxygen-induced toxicity
CE Helt et al.
TOXICOLOGICAL SCIENCES (2001)
Zinc binding and redox control of p53 structure and function
P Hainaut et al.
ANTIOXIDANTS & REDOX SIGNALING (2001)
Oxygen-mediated regulation of gelatinase and tissue inhibitor of metalloproteinases-1 expression by invasive cells
MT Canning et al.
EXPERIMENTAL CELL RESEARCH (2001)
The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress
MA O'Reilly et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)
ORP150 protects against hypoxia/ischemia-induced neuronal death
M Tamatani et al.
NATURE MEDICINE (2001)
Copper activation of superoxide dismutase 1 (SOD1) in vivo -: Role for protein-protein interactions with the copper chaperone for SOD1
PJ Schmidt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Antioxidant/pro-oxidant equilibrium regulates HIF-1α and NF-κB redox sensitivity -: Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
JJE Haddad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase
PC Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)