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Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
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Edg8/S1P5: An oligodendroglial receptor with dual function on process retraction and cell survival
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JOURNAL OF NEUROSCIENCE (2005)
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes
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Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells
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Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors
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Sphingosine-1-phosphate: An enigmatic signalling lipid
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Regulation of STAT3 activity by G16-coupled receptors
EHT Wu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
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MOLECULAR AND CELLULAR BIOLOGY (2003)
Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors
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MOLECULAR AND CELLULAR BIOLOGY (2003)
Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Edg-8 receptors are preferentially expressed in oligodendrocyte lineage cells of the rat CNS
K Terai et al.
NEUROSCIENCE (2003)
Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility
JL Tilly et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)
Characterization of a human sphingosine-1-phosphate receptor gene (S1P5) and its differential expression in LGL leukemia
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BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2002)
The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving Gi proteins and phosphatidylinositol-3 kinase
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ENDOCRINOLOGY (2002)
Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells
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EXPERIMENTAL CELL RESEARCH (2002)
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of Ras and mitogen-activated protein kinases
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MOLECULAR AND CELLULAR BIOLOGY (2002)
Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis
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Sphingosine 1-phosphate, a key cell signaling molecule.
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The Edg family G protein-coupled receptors for lysophospholipids: Their signaling properties and biological activities
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JOURNAL OF BIOCHEMISTRY (2002)
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
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SCIENCE (2002)
Involvement of sphingosine kinase in TNF-α-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells
LR Vann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of murine sphingosine-1-phosphate phosphohydrolase
H Le Stunff et al.
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Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Extracellular export of sphingosine kinase-1 enzyme - Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation
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YG Shi
MOLECULAR CELL (2002)
Moonlighting functions of polypeptide elongation factor 1: From actin bundling to zinc finger protein R1-associated nuclear localization
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BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria
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BLOOD (2001)
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Pulmonary lipid phosphate phosphohydrolase in plasma membrane signalling platforms
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BIOCHEMICAL JOURNAL (2001)
Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration
MJ Kluk et al.
CIRCULATION RESEARCH (2001)
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LPB3/EDG-3
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis
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MOLECULAR CELL (2001)
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EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Differential regulation of sphingosine-1-phosphate and VEGF-induced endothelial cell chemotaxis -: Involvement of Giα2-linked rho kinase activity
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AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)
Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence
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EXPERIMENTAL CELL RESEARCH (2001)
G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of αvβ3- and β1-containing integrins
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Drought-induced guard cell signal transduction involves sphingosine-1-phosphate
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NATURE (2001)
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility
JP Hobson et al.
SCIENCE (2001)
Nrg-1 belongs to the endothelial differentiation gene family of G protein-coupled sphingosime-1-phosphate receptors
RL Malek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3
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MOLECULAR AND CELLULAR BIOLOGY (2000)
Cell biology - Autophagy as a regulated pathway of cellular degradation
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SCIENCE (2000)
An oncogenic role of sphingosine kinase
P Xia et al.
CURRENT BIOLOGY (2000)
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
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Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22
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Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1-phosphate and induces cell death
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform
H Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins
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EMBO JOURNAL (2000)
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8
DS Im et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
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