期刊
CANCER AND METASTASIS REVIEWS
卷 28, 期 1-2, 页码 185-195出版社
SPRINGER
DOI: 10.1007/s10555-009-9184-9
关键词
Aurora Kinase; Mitosis; Anti-mitotic; Cell-cycle; Cancer; Therapeutic
类别
资金
- Cancer Research UK
In this article we review the basis for current anti-mitotic, anti-cancer, therapy and the potential for Aurora B kinase inhibitors as a new differentiated class of agents-mitotic drivers. We review the current understanding of Aurora B inhibition from basic cell biology to inhibitors currently undergoing clinical trials.
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