期刊
CANCER AND METASTASIS REVIEWS
卷 27, 期 4, 页码 575-587出版社
SPRINGER
DOI: 10.1007/s10555-008-9148-5
关键词
proliferation; DNA synthesis; thymidine kinase; thymidylate synthase; thymidine phosphorylase; thymidine; FMAU; FBAU; FAU
类别
资金
- National Cancer Institute [CA 83131, CA39566]
- Department of Defense [W81XWH-04-1-0140]
- [U24 92871]
Non-specific targets such as DNA and microtubules have been the mainstay of cancer therapeutics and the most effective clinical agents until a decade ago. Advances in genetics, molecular and cellular biology over the past decade led to the development of a new generation of agents that are far more specific and effective. In contrast to progress seen with therapeutic agents, general monitoring targets such as proliferation imaging are just gaining momentum and targeted imaging is still in its infancy. In these paradoxical times, this review assesses the role of proliferation imaging in monitoring the efficacy of targeted therapeutics.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据