期刊
CANCER
卷 120, 期 -, 页码 1097-1105出版社
WILEY-BLACKWELL
DOI: 10.1002/cncr.28574
关键词
recruitment; clinical trials; cancer; minority
类别
资金
- National Institute on Minority Health and Health Disparities [EMPaCT I, RC2MD00497, EMPaCT II, U24MD006970]
- National Cancer Institute [U54CA153499]
BACKGROUNDThe study of disparities in minority recruitment to cancer clinical trials has focused primarily on inquiries among minority populations. Yet very little is known about the perceptions of individuals actively involved in minority recruitment to clinical trials within cancer centers. Therefore, the authors assessed the perspectives of cancer center clinical and research personnel on barriers and facilitators to minority recruitment. METHODSIn total, 91 qualitative interviews were conducted at 5 US cancer centers among 4 stakeholder groups: cancer center leaders, principal investigators, research staff, and referring clinicians. All interviews were recorded and transcribed. Qualitative analyses of response data was focused on identifying prominent themes related to barriers and facilitators to minority recruitment. RESULTSThe perspectives of the 4 stakeholder groups were largely overlapping with some variations based on their unique roles in minority recruitment. Four prominent themes were identified: 1) racial and ethnic minorities are influenced by varying degrees of skepticism related to trial participation, 2) potential minority participants often face multilevel barriers that preclude them from being offered an opportunity to participate in a clinical trial, 3) facilitators at both the institutional and participant level potentially encourage minority recruitment, and 4) variation between internal and external trial referral procedures may limit clinical trial opportunities for racial and ethnic minorities. CONCLUSIONSMultilevel approaches are needed to address barriers and optimize facilitators within cancer centers to enhance minority recruitment for cancer clinical trials. Cancer 2014;120(7 suppl):1097-105. (c) 2014 American Cancer Society. Cancer center clinical and research personnel report unique experiences and perspectives on barriers and facilitators to minority recruitment. The input from these stakeholder groups may inform future approaches aimed at increasing minority enrollment.
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