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Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals
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Martin R. Tremblay et al.
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Hua Tian et al.
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Kenneth P. Olive et al.
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Suzie J. Scales et al.
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Jin Jiang et al.
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Hedgehog-Induced Survival of B-Cell Chronic Lymphocytic Leukemia Cells in a Stromal Cell Microenvironment: A Potential New Therapeutic Target
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A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch et al.
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Robert J. Lipinski et al.
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Inhibition of osteosarcoma cell proliferation by the hedgehog-inhibitor cyclopamine
J. Warzecha et al.
JOURNAL OF CHEMOTHERAPY (2007)
Essential role of stromally induced hedgehog signaling in B-cell malignancies
Christine Dierks et al.
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Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists
Matthias Lauth et al.
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Purmorphamine activates the Hedgehog pathway by targeting Smoothened
S Sinha et al.
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Altered expression and deletion of RM01 in osteosarcoma
K Eppert et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Hedgehog signaling promotes prostate xenograft tumor growth
L Fan et al.
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C Thibert et al.
SCIENCE (2003)
Small molecule modulation of Smoothened activity
JK Chen et al.
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Hedgehog regulates cell growth and proliferation by inducing cyclin D and cyclin E
M Duman-Scheel et al.
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Prognostic factors in high-grade osteosarcoma of the extremities or trunk:: An analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols
SS Bielack et al.
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J Taipale et al.
NATURE (2000)
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