期刊
CANCER
卷 117, 期 10, 页码 2250-2257出版社
WILEY
DOI: 10.1002/cncr.26051
关键词
adolescents; young adults; cancer; survivor; late effects; risk-based healthcare
类别
资金
- Health Canada through the Canadian Partnership Against Cancer
- C17
- Advisory Board of the Institute for Cancer Research at the Canadian Institutes for Health Research (CIHR)
- Public Health Agency of Canada
- Ontario Institute for Cancer Research
- CIHR
- Terry Fox Research Institute
- LIVESTRONG, formerly the Lance Armstrong Foundation
- Canadian Cancer Society Research Institute
- Young Adult Cancer Canada
- Hope and Cope
- Comprehensive Cancer Centre at the Hospital for Sick Children, Toronto
- Canadian Partnership Against Cancer
About 26,000 adolescents and young adults ages 15 to 29 years are diagnosed with invasive cancer each year. Although > 80% will survive beyond 5 years from their cancer diagnosis: many will develop serious morbidity or die prematurely secondary to health problems in part related to their cancer therapy. This article provides a brief overview of mortality, morbidity, and health status among long-term survivors of adolescent and young adult (AYA) cancer. Four examples were used to illustrate the potential of risk-reducing strategies: breast cancer after chest irradiation, coronary artery disease after chest irradiation, cardiovascular disease in testicular cancer survivors, and the multitude of health problems faced by survivors receiving an allogeneic hematopoietic stem cell transplant. A conceptual model for risk-based health care was presented and future directions of the delivery of care for AYA cancer survivors discussed. Cancer 2011;117(10 Suppl):2250-7. (C) 2011 American Cancer Society.
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