期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 13, 期 23, 页码 6745-6754出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200700306
关键词
aziridines; hypervalent compounds; iodine; reaction mechanism; oxidation
资金
- Engineering and Physical Sciences Research Council [GR/S73105/01] Funding Source: researchfish
By detailed study of the possible side reactions in the previously reported aziridination of alkenes with N-aminoheterocycles mediated by hypervalent iodine reagents, the requirements to make this reaction catalytic in iodoarene have been determined. The reaction requires an oxidant that will oxidise iodoarenes but that does not oxidise alkenes, but it is possible that no such oxidant actually exists! A method in which the hypervalent iodine reagent can be recycled without the need for reisolation is possible. Further study into the mechanism of this reaction gives tentative evidence that the reaction proceeds through formation of an aminoiodane that reacts directly with the alkene, contrary to previous literature reports in which an acetoxyamine intermediate is suggested. The temperature effect of this reaction is remarkable.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据