期刊
NEUROIMAGE
卷 35, 期 2, 页码 949-958出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2006.11.041
关键词
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资金
- NIA NIH HHS [K01 AG027369] Funding Source: Medline
- NIMH NIH HHS [MH64295, F32 MH064295] Funding Source: Medline
- NINDS NIH HHS [R01 NS045171, NS45171, NS27900, R01 NS027900] Funding Source: Medline
- NATIONAL INSTITUTE OF MENTAL HEALTH [F32MH064295] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS045171, R01NS027900] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [K01AG027369] Funding Source: NIH RePORTER
Attentional control involves the ability to allocate preparatory attention to improve subsequent stimulus processing and response selection. There is behavioral evidence to support the hypothesis that increased expectancy of stimulus and response conflict may decrease the subsequent experience of conflict during task performance. We used a cued flanker and event-related fMRI design to separate processes involved in preparation from those involved in resolving conflict and to identify the brain systems involved in these processes as well as the association between preparatory activity levels and activity related to subsequent conflict processing. Our results demonstrate that preparatory attentional allocation following a cue to the upcoming level of conflict is mediated by a network involving Dorsolateral Prefrontal Cortex (DLPFC) and the Intraparietal Sulcus (IPS). Informed preparation for conflict processing was associated with decreased Anterior Cingulate Cortex/pre-Supplementary Motor Area (ACC/pre-SMA) and IPS activity during the flanker target presentation, supporting their roles in conflict processing and visuospatial attention during the flanker task. Ventrolateral Prefrontal Cortex/Orbitofrontal Cortex (VLPFC/OFC) was active when specific strategic task rule and outcome information was available. (c) 2006 Elsevier Inc. All rights reserved.
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