期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 5, 期 18, 页码 2913-2915出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b711164a
关键词
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Highly enantioselective aldol reactions of aldehydes with cyclic ketones catalyzed by a primary amine derived from cinchonine are reported. Aromatic aldehydes reacted with various cyclic ketones cleanly to afford the anti-aldol adducts in up to 99% yield, with good diastereoselectivities ( up to 9:1) and excellent enantioselectivities ( up to 99% ee).
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