期刊
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
卷 297, 期 5, 页码 307-319出版社
ELSEVIER GMBH
DOI: 10.1016/j.ijmm.2007.03.008
关键词
Helicobacter pyloril lipopolysccharide; lipid a; lewis antigens; innate immune response; toll-like receptors
Lipopolysaccharides are generally considered toxic components of the Gram-negative bacterial outer membrane with potent immunomodulating and immunostimulating properties, but their contribution to adaptation of a given bacterial species to its microbial niche is, however, predominantly overlooked. Helicobacter pylori, as a cause of longterm infection in the gastroduodenal tract, has been proposed as a model for investigating and understanding the dynamics of bacterial persistence and parasitism in chronic infections. This review examines the structure and properties of H. pylori lipopolysaccharide and its lipid A moiety, and the insights that have been gained into their contribution to chronic infection and pathogenesis, including evasion and dampening of innate immune responses. (c) 2007 Elsevier GmbH. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据