期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 117, 期 3, 页码 530-538出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI30595
关键词
-
资金
- NHLBI NIH HHS [P50 HL056402, R01 HL069865, R01 HL073728, R01 HL69865, P50 HL56402] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL069865, P50HL056402, R01HL073728] Funding Source: NIH RePORTER
The unrelenting and destructive progression of most fibrotic responses in the pulmonary, cardiovascular, integumentary, and alimentary systems remains a major medical challenge for which therapies are desperately needed. The pathophysiology of fibrosis remains an enigma, but considerable research and debate surrounds the question of whether chronic inflammation is the key driver of unrestrained wound healing (i.e., the fibrotic response) in these and other organ systems. This Review describes how infectious pathogens, chronic inflammation, and unrestrained fibroproliferation are likely to be part of a dynamic, unrelenting process propelling human fibrotic diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据