期刊
SYNTHETIC COMMUNICATIONS
卷 37, 期 15, 页码 2593-2599出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910701462922
关键词
acetylenedicarboxylates; aqueous glucose; dimethylurea; hexahydropyrimidine; isocyanide; three-component reaction
An effective route to novel 2,6-dioxohexahydropyrimidines is described. This involves reaction of alkyl isocyanides and dialkyl acetylenedicarboxylates in the presence of N, N'-dimethylurea in 1M aq. glucose.
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