期刊
AMINO ACIDS
卷 33, 期 3, 页码 459-462出版社
SPRINGER
DOI: 10.1007/s00726-006-0447-2
关键词
plasma membrane; fluorescence anisotropy; surfactants; erythrocyte; arginine; lysine
In an attempt to increase our knowledge regarding the mechanisms of surfactant membrane interaction, we studied the action of several anionic and cationic amino acid-based surfactants on membrane fluidity using fluorescence anisotropy. Anisotropy measurements demonstrated that almost all of the surfactants studied disturbed the external region of the erythrocyte membrane without affecting the core of the bilayer. How the physico-chemical properties and structure of these compounds affect dynamics of the lipid bilayer is discussed in detail.
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