期刊
HAEMATOLOGICA
卷 92, 期 4, 页码 570-571出版社
FERRATA STORTI FOUNDATION
DOI: 10.3324/haematol.10770
关键词
doxorubicin; carrier erythrocytes; pharmacokinetics; lymphoma
类别
Doxorubicin-loaded erythrocytes (DLE) were administrated to 15 lymphoma patients. Antibiotic peak concentration in blood decreased by 55%, doxorubicin circulated several times longer, and the area under the concentration-time curve increased 5 times if compared with standard doxorubicin administration. The DLE was well tolerated by patients.
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