期刊
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
卷 69, 期 -, 页码 3-9出版社
WILEY-LISS
DOI: 10.1002/prot.21767
关键词
protein structure prediction; community wide experiment; CASP
资金
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R13GM072354] Funding Source: NIH RePORTER
- NIGMS NIH HHS [GM072354] Funding Source: Medline
- NLM NIH HHS [LM07085] Funding Source: Medline
- Wellcome Trust [077198] Funding Source: Medline
This paper is an introduction to the supplemental issue of the journal PROTEINS, dedicated to the seventh CASP experiment to assess the state of the art in protein structure prediction. The paper describes the conduct of the experiment, the categories of prediction included, and outlines the evaluation and assessment procedures. Highlights are improvements in model accuracy relative to that obtainable from knowledge of a single best template structure; convergence of the accuracy of models produced by automatic serve, toward that produced by human modeling teams; the emergence of methods for predicting the quality of models; and rapidly increasing practical application of the methods.
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