期刊
CLINICAL NEUROPHYSIOLOGY
卷 118, 期 1, 页码 111-118出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.clinph.2006.09.024
关键词
H-reflex; low back pain; presynaptic inhibitions; homosynaptic depression; motoneurone
Objective: We investigated whether patients with chronic low back pain (CLBP) manifest changes in the excitability of the soleus H-reflex. Methods: H-reflex stimulus-response curve was studied in 14 CLBP patients and 14 age-matched healthy subjects. H-threshold, H-maximum size, H-steepness and H-latency were determined for both legs. Homosynaptic depression (HD), following a train of H-reflexes, and presynaptic inhibition (PI) from flexor afferents onto soleus la afferents were also evaluated. Results: H-threshold was significantly increased, H-size as a function of stimulus intensity was significantly different, and H-recruitment curve steepness was significantly lower in CLBP patients compared to healthy subjects. No significant difference in the amount of HD and PI of the H-reflex was found between the two groups. H-latency and H-max/M-max ratio was comparable between the subjects groups. Conclusions: In CLBP there is a reduced excitability of group la afferent fibres from the soleus muscle to which presynaptic factors do not seem to contribute and that presumably depend on changes in the peripheral sensory input. Significance: Changes in H-reflex excitability may underlie a decrease in the gain of a peripheral sensor in CLBP. Estimation of soleus H-threshold and H-recruitment curve may contribute to the diagnostic evaluation of CLBP and may be used to monitor the efficacy of treatment. (c) 2006 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
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