Polydentate Schiff-base ligands and their Cd(II) and Cu(II) metal complexes: synthesis, characterization, biological activity and electrochemical properties

Synthesis, characterization, microbiological activity and electrochemical properties of the Schiff-base ligands A(1)-A(5) and their Cd(II) and Cu(II) metal complexes are reported. The ligands and their complexes have been characterized by elemental analysis, FT-IR, UV-Vis, H-1- and C-13-NMR, mass spectra, magnetic susceptibility and conductance measurements. In the complexes, all the ligands are bidentate, the oxygen in the ortho position and azomethine nitrogen atoms of the ligands coordinate to the metal ions. The keto-enol tautomeric forms of the Schiff-base ligands A(1)-A(5) have been investigated in polar and non-polar organic solvents. Antimicrobial activity of the ligands and metal complexes were tested using the disc diffusion method and the chosen strains include Bacillus megaterium and Candida tropicalis. The electrochemical properties of the ligands A(1)-A(5) and their Cu( II) metal complexes have been investigated at different scan rates (100-500mVs(-1)) in DMSO.