期刊
CEREBRAL CORTEX
卷 18, 期 1, 页码 230-242出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cercor/bhm049
关键词
default mode; narrative speech comprehension
资金
- NCRR NIH HHS [RR12169, RR13642, RR00865] Funding Source: Medline
- NIMH NIH HHS [MH63680] Funding Source: Medline
- NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR013642, M01RR000865, C06RR012169] Funding Source: NIH RePORTER
The role of superior temporal cortex in speech comprehension is well established, but the complete network of regions involved in understanding language in ecologically valid contexts is less clearly understood. In a functional magnetic resonance imaging (fMRI) study, we presented 24 subjects with auditory or audiovisual narratives, and used model-free intersubject correlational analyses to reveal brain areas that were modulated in a consistent way across subjects during the narratives. Conventional comparisons to a resting state were also performed. Both analyses showed the expected recruitment of superior temporal areas, however, the intersubject correlational analyses also revealed an extended network of areas involved in narrative speech comprehension. Two findings stand out in particular. Firstly, many areas in the default mode network (typically deactivated relative to rest) were systematically modulated by the time-varying properties of the auditory or audiovisual input. These areas included the anterior cingulate and adjacent medial frontal cortex, and the posterior cingulate and adjacent precuneus. Secondly, extensive bilateral inferior frontal and premotor regions were implicated in auditory as well as audiovisual language comprehension. This extended network of regions may be important for higher-level linguistic processes, and interfaces with extralinguistic cognitive, affective, and interpersonal systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据