期刊
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
卷 38, 期 8, 页码 1474-1484出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-007-0526-6
关键词
autism spectrum disorders; schizophrenia; thought disorder; executive functions; anxiety
资金
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [K12HD051958] Funding Source: NIH RePORTER
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [U19HD035468] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH068398, K02MH064190, K08MH074967] Funding Source: NIH RePORTER
This study investigated whether children with autism spectrum disorders (ASDs) exhibit formal thought disorder (FTD), and whether this is related to ASD symptoms, executive control, and anxiety. Participants aged 8-17 with ASDs exhibited significantly more illogical thinking and loose associations than matched typically developing control subjects. In participants with ASDs, illogical thinking was related to aspects of cognitive functioning and to executive control. Loose associations were related to autism communication symptoms and to parent reports of stress and anxiety. When FTD is present in ASDs, it generally is not a co-morbid schizophrenia symptom, but is related to pragmatic language abnormalities found in ASDs. The clinical and neurobiological significance of this work is discussed.
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