4.7 Article

A stochastic SIRS epidemic model with infectious force under intervention strategies

期刊

JOURNAL OF DIFFERENTIAL EQUATIONS
卷 259, 期 12, 页码 7463-7502

出版社

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.jde.2015.08.024

关键词

Epidemic model; Markov semigroups; Reproduction number; Stationary distribution

资金

  1. National Science Foundation of China [61373005]
  2. Zhejiang Provincial Natural Science Foundation, China [LY12A01014]
  3. NSF-DMS [1313312]
  4. Simons Collaboration Grants for Mathematicians [208902]
  5. College of Letters and Sciences

向作者/读者索取更多资源

In this paper, we extend a classical SIRS epidemic model with the infectious forces under intervention strategies from a deterministic framework to a stochastic differential equation (SDE) one through introducing random fluctuations. The value of our study lies in two aspects. Mathematically, by using the Markov semigroups theory, we prove that the reproduction number R-0(S) can be used to govern the stochastic dynamics of SDE model If R-0(S) < 1, under mild extra conditions, the SDE system has a disease-free absorbing set which means the extinction of disease with probability one. If R-0(S) > 1, under mild extra conditions, it has an endemic stationary distribution which leads to the stochastical persistence of the disease. Epidemiologically, we find that random fluctuations can suppress disease outbreak, which can provide us some useful control strategies to regulate disease dynamics. (C) 2015 Elsevier Inc. All rights reserved.

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