期刊
SUPPORTIVE CARE IN CANCER
卷 16, 期 3, 页码 229-234出版社
SPRINGER
DOI: 10.1007/s00520-007-0367-z
关键词
cachexia; cancer; biomarkers; genetics; polymorphisms
资金
- Medical Research Council [G0700711B] Funding Source: researchfish
Introduction Cancer cachexia is a severe debilitating disorder, which causes significant morbidity and mortality. In clinical practice, cachexia is often not treated until a late stage, when therapeutic options are limited. Objective It is therefore of great interest to analyse early biomarkers of this syndrome. Conclusion In this review article, we summarise recent biomarkers found in various body compartments. We also explore the likelihood of a genetic predisposition to cachexia and focus on the potential role of single nucleotide polymorphisms in genes coding for pro- and anti-inflammatory cytokines, and 'atrogenes' associated with wasting in skeletal muscle.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据