期刊
JOURNAL OF DIABETES AND ITS COMPLICATIONS
卷 29, 期 3, 页码 445-450出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jdiacomp.2014.12.006
关键词
Incretin hormones; Glucagon-like peptide-1; Glucose-dependent insulinotropic peptide; ELISA; RIA
资金
- NNF Center for Basic Metabolic Research [Holst Group] Funding Source: researchfish
- Novo Nordisk Fonden [NNF14OC0013563] Funding Source: researchfish
The two incretin hormones, glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), are secreted from the gastrointestinal tract in response to meals and contribute to the regulation of glucose homeostasis by increasing insulin secretion. Assessment of plasma concentrations of GLP-1 and GIP is often an important endpoint in both clinical and preclinical studies and, therefore, accurate measurement of these hormones is important. Here, we provide an overview of current approaches for the measurement of the incretin hormones, with particular focus on immunological methods. (C) 2015 Elsevier Inc. All rights reserved.
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