期刊
JOURNAL OF DIABETES AND ITS COMPLICATIONS
卷 29, 期 8, 页码 1066-1070出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jdiacomp.2015.06.014
关键词
Type 2 diabetes mellitus; Somatic neuropathy; BMI; HbA1c; Complications
Aims: Somatic neuropathy is a chronic complication of diabetes. The purpose of our study was to determine prevalence and clinical variables associated with somatic neuropathy applying a simple screening method. Methods: All outpatients with type 2 diabetes attending our diabetic clinic were offered to participate into a diabetic foot screening program, in the period January 2004-December 2012. A total of 3,591 diabetic patients (55.5% men, age 68 +/- 10 years) underwent detection of somatic neuropathy using the Michigan Neuropathy Screening Instrument in its parts of symptoms (administering a questionnaire) and clinical assessment slightly modified (evaluating foot inspection, vibration sensation by biothesiometer, ankle reflexes). Results: The prevalence of somatic neuropathy was 2.2% in men and 5.5% in women (p < 0.001) when assessed by symptom questionnaire, whereas it was 30.5% in men and 30.8% (p = NS) in women when identified by clinical assessment. In subjects with somatic neuropathy macro- and microvascular complications of diabetes were significantly more common. In multivariate logistic regression analyses BMI, HbA1c and ankle/brachial index independently predicted the presence of neuropathy. Conclusion: The prevalence of somatic neuropathy in type 2 diabetes is nearly 30% when searched with clinical examination. Poor metabolic control, excess body weight and peripheral arteriopathy are independent markers of somatic neuropathy. (C) 2015 Elsevier Inc. All rights reserved.
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