期刊
JOURNAL OF DENTAL RESEARCH
卷 94, 期 11, 页码 1495-1501出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0022034515603972
关键词
mesenchymal stromal cells; neural crest; hedgehogs; Gli1 protein; skull; stem cell niche
资金
- National Institute of Dental and Craniofacial Research, National Institutes of Health [R90 DE022528, R37 DE012711, R01 DE022503, U01 DE024421]
Stem cells are remarkable, and stem cell-based tissue engineering is an emerging field of biomedical science aiming to restore damaged tissue or organs. In dentistry and reconstructive facial surgery, it is of great interest to restore lost teeth or craniofacial bone defects using stem cell-mediated therapy. In the craniofacial region, various stem cell populations have been identified with regeneration potential. In this review, we provide an overview of the current knowledge concerning the various types of tooth- and craniofacial bone-related stem cells and discuss their in vivo identities and regulating mechanisms.
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