期刊
BONE MARROW TRANSPLANTATION
卷 41, 期 2, 页码 193-198出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bmt.1705906
关键词
EBV; CMV; adenovirus
资金
- NCI NIH HHS [P01 CA94237] Funding Source: Medline
- NCRR NIH HHS [RR00188] Funding Source: Medline
- NHLBI NIH HHS [U54HL081007] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [P01CA094237] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [U54HL081007] Funding Source: NIH RePORTER
Viral infections remain a major cause of morbidity and mortality after pediatric hematopoietic stem cell transplantation. Adoptive transfer of donor-derived virusspecific T cells can reconstitute antiviral immunity in recipients and be effective both in preventing and treating cytomegalovirus, Epstein-Barr virus and adenovirus infection. Current efforts are focused on providing protection toward a broader range of viruses safely, rapidly and effectively.
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