期刊
BULLETIN OF MATHEMATICAL BIOLOGY
卷 70, 期 4, 页码 1098-1114出版社
SPRINGER
DOI: 10.1007/s11538-007-9292-z
关键词
Ross-Macdonald model; malaria transmission; incubation period; time delay; basic reproduction number
The feedback dynamics from mosquito to human and back to mosquito involve considerable time delays due to the incubation periods of the parasites. In this paper, taking explicit account of the incubation periods of parasites within the human and the mosquito, we first propose a delayed Ross-Macdonald model. Then we calculate the basic reproduction number R-0 and carry out some sensitivity analysis of R-0 on the incubation periods, that is, to study the effect of time delays on the basic reproduction number. It is shown that the basic reproduction number is a decreasing function of both time delays. Thus, prolonging the incubation periods in either humans or mosquitos (via medicine or control measures) could reduce the prevalence of infection.
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