期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 156, 期 4, 页码 504-508出版社
SPRINGER
DOI: 10.1007/s10517-014-2385-4
关键词
coral aquacultures; cytocompatibility; biocompatibility; tissue engineering construct; multipotent mesenchymal stromal cells
资金
- Russian Foundation for Basic Research [13-03-12127ofi-m]
Cytocompatibility of 5 coral aquaculture skeleton species derived from two families (Acroporidae and Pocilloporidae) was studied over the course of in vitro culturing in continuous human fibroblast culture by the MMT test. Biocompatibility and capacity of scaffold to transfer cell cultures (specifically, multipotent mesenchymal stromal cells) to sites of implantation were studied in vivo by subcutaneous implantation of skeletal fragments to rats. All coral skeleton aquaculture specimens were cytocompatible (nontoxic and with surface matrix characteristics satisfactory for cells), biocompatible, and could be tried as 3D matrices for bone tissue engineering.
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