期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 156, 期 5, 页码 665-668出版社
SPRINGER
DOI: 10.1007/s10517-014-2421-4
关键词
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We compared anti-inflammatory activity of individual diterpene alkaloids isolated from Aconitum baikalense (napelline, songorine, hypaconitine, mesaconitine, 12-epinapelline N-oxide) under conditions of acute inflammation of different genesis. The tested substances showed high antiexudative activity comparable with that of sodium diclofenac. Unlike nonsteroidal anti-inflammatory drugs, diterpene alkaloids exerted no ulcerogenic effect.
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