期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 156, 期 4, 页码 560-565出版社
SPRINGER
DOI: 10.1007/s10517-014-2396-1
关键词
mesenchymal stem cells; human bone marrow; osteogenic differentiation; differentiation markers; platelet releasate
We studied the effect of platelet releasate on osteogenic differentiation of human mesenchymal BM stem cells. Histological staining and reverse transcription PCR analysis showed that addition of platelet releasate to osteogenic differentiation medium stimulated the formation of calcium ossificates and alkaline phosphatase and increased expression of osteopontin and alkaline phosphatase genes.
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