期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 151, 期 3, 页码 370-373出版社
SPRINGER
DOI: 10.1007/s10517-011-1333-9
关键词
osteonectin; CD34; stenosing atherosclerosis; coronary artery calcinosis; atherosclerosis biomarkers
资金
- Russian Foundation for Basic Research [09-04-00374]
Blood levels of stem cell marker proteins CD34 and osteonectin were studied in male patients with coronary atherosclerosis by direct biomagnetic separation of proteins with magnetic microspheres using the PureProteome Protein A and Protein G Magnetic Beads proteomic technology. High concentration of osteonectin in the blood was detected, particularly in men with stenosing atherosclerosis and coronary artery calcinosis. Blood osteonectin concentration correlated significantly with some key biomarkers of atherosclerosis and with stenosing atherosclerosis and calcinosis of coronary arteries. The results indicate that osteonectin as a marker of stromal stem cells with osteogenic potential presumably plays an important role in atherogenesis and can serve as a new biomarker of stenosing atherosclerosis and calcinosis of coronary arteries.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据