期刊
ANALYTICAL METHODS
卷 7, 期 1, 页码 296-300出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ay02297a
关键词
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资金
- National Natural Science Foundation of China [21375036]
- Hunan Provincial Natural Science Foundation of China [14JJ7054]
- Innovation Platform Open Funds for Universities in Hunan Province [13K090]
- Innovation Foundation of Graduate Student of Hunan University of Science and Technology [S130028]
In this study, a fluorescence assay for the successive determination of Fe3+ and Cu2+ ions based on the quenching fluorescence of composite AuAg nanoclusters (AuAg NCs) was developed. Using this binary fluorescence sensor, the Fe(III) level in a human serum sample can be directly detected without pretreatment. After the nitrification of human serum, the bio-copper level in human serum may be measured with a quick response. Human serum samples were analyzed, and the average concentration of Fe(III) and bio-copper were found to be 2.33 x 10(-5) and 2.91 x 10(-5) M, respectively. This assay was not only sensitively responsive to blood iron(III) but also to serum copper, suggesting significant potential applications for successively monitoring the Fe(III) and bio-copper levels, and their changes during the progression of a biological process.
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