期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 147, 期 6, 页码 715-718出版社
SPRINGER
DOI: 10.1007/s10517-009-0596-x
关键词
paclitaxel; spermatogenesis; rats
Morphological and functional characteristics of spermatogenesis in rats were studied during the early and delayed periods after single injection of paclitaxel (antitumor agent) in the maximum tolerated dose. The drug induced structural changes in the gonads associated with oligospermia and increased number of pathological forms of spermatozoa with reduced functional activity.
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