期刊
JOURNAL OF CRANIOFACIAL SURGERY
卷 26, 期 5, 页码 1711-1712出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/SCS.0000000000001857
关键词
Eccrine spiradenoma; malignant spiradenoma; spiradenocarcinoma; spiradenoma
类别
Malignant eccrine spiradenoma, or spiradenocarcinoma, is an exceedingly rare sweat-gland tumor, with only 102 reported cases. Low-grade carcinomas are especially rare with only a few cases reported. Because of the limited number of case reports, the biologic behavior of low-grade malignant eccrine spiradenoma is poorly understood and no evidence-based therapeutic approach is established. Here, the authors report a 29-year-old woman who presented with a history of left-sided facial lesions present since the age of 2 months. Histopathologic examination revealed multiple benign spiradenomas, several of which showed foci of low-grade malignant transformation evidenced by loss of the characteristic 2-cell population seen in the benign tumor component. Included are the clinical presentation, histopathologic description, and surgical decision making in an effort to guide recognition of this rare entity.
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