期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 146, 期 3, 页码 344-347出版社
SPRINGER
DOI: 10.1007/s10517-008-0293-1
关键词
aneuploidy; FISH; interphase cells; stem cells
资金
- Russian Foundation for Basic Research [06-04-49135-a, 07-04-12157-ofi]
- President of the Russian Federation [NSh-1006.2006.7, 02.512.11.2135]
The incidence of autosomes 6 and 8 aneuploidy in stem cell cultures derived from adipose tissue was evaluated at different stages of culturing. Monosomy was more incident than trisomy during the early passages. Distribution of cultures by the incidence of aneuploidy in different chromosomes was virtually the same. Clones with chromosome 6 monosomy were detected in two cultures during late passages.
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