期刊
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
卷 145, 期 6, 页码 688-691出版社
SPRINGER
DOI: 10.1007/s10517-008-0174-7
关键词
ischemia; retina; experimental model; rats
资金
- Russian Foundation for Basic Research [05-04-49223-a]
We studied the development of retinal ischemia in rat eye after laser coagulation of blood vessels. Typical signs of ischemia manifested in the retina after 24 h: development of stable retinal edema, decrease in the b/a index (ratio of the electroretinogram b and awave amplitudes) to 1-2 units, pronounced disorders in the retinal microcirculation system, leading to ischemia of the inner layers of the retina. The proposed model is convenient for studies of the development of acute retinal ischemia, is easily realized, and reproduces some acute ischemic diseases of the retina.
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