期刊
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
卷 89, 期 6, 页码 1148-1153出版社
SPRINGER
DOI: 10.1007/s00128-012-0837-y
关键词
Cadmium; Biochemical responses; Long exposure; CYP; Antioxidant enzymes; GST
资金
- National Natural Science Foundation of China [20977094, 40930739]
- Ministry of Science and Technology of China [2012BAD14B02]
The biochemical responses of the earthworms, Eisenia fetida, exposed to a series of Cd concentrations (0.00, 1.25, 2.50, 5.00 and 10.00 mg Cd2+ kg(-1) soil) for up to 8 weeks were investigated, aiming to evaluate the sublethal effects of Cd with long exposure and to explore the potential for applying these responses as biomarkers to indicate the Cd-contaminated soil. The following biochemical parameters were determined: cytochrome P450 (CYP) contents and activities of superoxide dismutase (SOD), catalase (CAT) and glutathione-s-transferase (GST). Cadmium concentrations in all earthworms were apparently accumulated in 4 weeks, and showed minor changes in weeks 6-8 compared to the first 4 weeks. CYP presented a significant elevation in 2-4 weeks and a decline in 6-8 weeks in each treated group. The activities of SOD and CAT showed an obvious increase with exposure of 6-8 weeks while their levels were not affected in 4 weeks in each treated group. GST activity revealed significant activation starting from week 4. This study confirmed the significance of applying a suite of biomarkers rather than a selective choice to assess the impact of pollutants on organisms. It also indicated that the observed effects were more dependent upon exposure duration than dose.
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