期刊
BRITISH JOURNAL OF SPORTS MEDICINE
卷 47, 期 11, 页码 692-696出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/bjsports-2012-091735
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资金
- Medical Research Council [G0801462] Funding Source: Medline
Background Vitamin D deficiency is common in the general public and athletic populations and may impair skeletal muscle function. We therefore assessed the effects of vitamin D-3 supplementation on serum 25[OH] D concentrations and physical performance. Methods 30 club-level athletes were block randomised (using baseline 25[ OH] D concentrations) into one of three groups receiving either a placebo (PLB), 20 000 or 40 000 IU/week oral vitamin D3 for 12 weeks. Serum 25 [OH] D and muscle function (1-RM bench press and leg press and vertical jump height) were measured presupplementation, 6 and 12 weeks postsupplementation. Vitamin D deficiency was defined in accordance with the US Institute of Medicine guideline (<50 nmol/l). Results 57% of the subject population were vitamin D deficient at baseline (mean +/- SD value 51 +/- 24 nmol/l). Following 6 and 12 weeks supplementation with 20 000 IU (79 +/- 14 and 85 +/- 10 nmol/l, respectively) or 40 000 IU vitamin D3 (98 +/- 14 and 91 +/- 24 nmol/l, respectively), serum vitamin D concentrations increased in all participants, with every individual achieving concentrations greater than 50 nmol/l. In contrast, vitamin D concentration in the PLB group decreased at 6 and 12 weeks (37 +/- 18 and 41 +/- 22 nmol/l, respectively). Increasing serum 25[OH] D had no significant effect on any physical performance parameter (p>0.05). Conclusions Both 20 000 and 40 000 IU vitamin D3 supplementation over a 6-week period elevates serum 25 [OH] D concentrations above 50 nmol/l, but neither dose given for 12 weeks improved our chosen measures of physical performance.
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