期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 203, 期 4, 页码 310-311出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.112.122838
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资金
- EMBARC [U01MH092221-01]
- NARSAD
- Wellcome Trust [WT086565/Z/08/Z]
- [R01 MH076971-01]
- [R01 MH084021]
- [DM090122]
- [1 U01MH092221-01]
- Medical Research Council [G0801418B] Funding Source: researchfish
Differentiating bipolar from recurrent unipolar depression is a major clinical challenge. In 18 healthy females and 36 females in a depressive episode - 18 with bipolar disorder type I, 18 with recurrent unipolar depression - we applied pattern recognition analysis using subdivisions of anterior cingulate cortex (ACC) blood flow at rest, measured with arterial spin labelling. Subgenual ACC blood flow classified unipolar v. bipolar depression with 81% accuracy (83% sensitivity, 78% specificity).
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