期刊
BRITISH JOURNAL OF PSYCHIATRY
卷 196, 期 2, 页码 139-142出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.109.067058
关键词
-
类别
资金
- Eli Lilly
- Servier
Background The impact of personality dysfunction on the outcome of treatment for depression remains debated. Aims To examine the relationship between the number of prior depressive episodes, personality dysfunction and treatment response for depression. Method In a large sample (n = 8229) of adult out-patients with a major depressive episode (DSM-IV), personality dysfunction was assessed using the Standardised Assessment of Personality Abbreviated Scale (SAPAS). Potential predictors of treatment response at 6 weeks were examined via structural equation modelling. Results The amount of personality dysfunction and number of prior episodes of depression were both associated with poor response to treatment. Once personality dysfunction was controlled for, the number of prior episodes of depression was not associated with treatment response. Conclusions Personality dysfunction is associated with impaired short-term response to antidepressant treatment in major depression. The apparent detrimental effect of prior depression on treatment response may be accounted for by pre-existing personality dysfunction,
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据