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F. Gautier et al.
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Ryuji Yamaguchi et al.
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Guidelines for reporting experiments involving animals: the ARRIVE guidelines
J. C. McGrath et al.
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Animal research: Reporting in vivo experiments: The ARRIVE guidelines
Carol Kilkenny et al.
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Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis
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ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
Christin Tse et al.
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Haiming Ding et al.
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J. M. Adams et al.
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