相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity
M. Lamar Seibenhener et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis
Manal A. Farg et al.
HUMAN MOLECULAR GENETICS (2013)
Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1
Sarah Pickles et al.
HUMAN MOLECULAR GENETICS (2013)
The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
Wenzhang Wang et al.
HUMAN MOLECULAR GENETICS (2013)
Small Peptides against the Mutant SOD1/Bcl-2 Toxic Mitochondrial Complex Restore Mitochondrial Function and Cell Viability in Mutant SOD1-Mediated ALS
Wenzhi Tan et al.
JOURNAL OF NEUROSCIENCE (2013)
Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
Philippe A. Parone et al.
JOURNAL OF NEUROSCIENCE (2013)
Controversies and priorities in amyotrophic lateral sclerosis
Martin R. Turner et al.
LANCET NEUROLOGY (2013)
A progressive translational mouse model of human valosin-containing protein disease: The VCPR155H/+ mouse
Angele Nalbandian et al.
MUSCLE & NERVE (2013)
The changing scene of amyotrophic lateral sclerosis
Wim Robberecht et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis
Yi Zhang et al.
NEUROBIOLOGY OF DISEASE (2013)
Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α
Wenjun Song et al.
NEUROBIOLOGY OF DISEASE (2013)
AIF, reactive oxygen species, and neurodegeneration: A complex problem
Brian M. Polster
NEUROCHEMISTRY INTERNATIONAL (2013)
Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels
Fernando Bartolome et al.
NEURON (2013)
Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study: Subgroup analysis of demographic and clinical characteristics
Stacy A. Rudnicki et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)
Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency
Kambiz N. Alavian et al.
BRAIN RESEARCH (2012)
Physiological Roles of the Permeability Transition Pore
Catherine Brenner et al.
CIRCULATION RESEARCH (2012)
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
Kurt J. De Vos et al.
HUMAN MOLECULAR GENETICS (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
Gabor M. Morotz et al.
HUMAN MOLECULAR GENETICS (2012)
Decreased mRNA Expression of PGC-1α and PGC-1α-Regulated Factors in the SOD1G93A ALS Mouse Model and in Human Sporadic ALS
Nadine Thau et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Mitochondria: master regulators of danger signalling
Lorenzo Galluzzi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line
Kun Hong et al.
NEUROSCIENCE LETTERS (2012)
Bim Links ER Stress and Apoptosis in Cells Expressing Mutant SOD1 Associated with Amyotrophic Lateral Sclerosis
Kai Y. Soo et al.
PLOS ONE (2012)
Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis
Petar Marinkovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
Robert G. Miller et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)
SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
Faisal Fecto et al.
ARCHIVES OF NEUROLOGY (2011)
Caspase-8 and Bid: Caught in the act between death receptors and mitochondria
Chahrazade Kantari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation
Maria Grazia Pesaresi et al.
HUMAN MOLECULAR GENETICS (2011)
Mitochondrial pathobiology in ALS
Lee J. Martin
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
Neurotoxic 43-kDa TAR DNA-binding Protein (TDP-43) Triggers Mitochondrion-dependent Programmed Cell Death in Yeast
Ralf J. Braun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis
Wei Zhao et al.
MOLECULAR NEURODEGENERATION (2011)
Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice
Ya-Fei Xu et al.
MOLECULAR NEURODEGENERATION (2011)
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
Jodi Meyerowitz et al.
MOLECULAR NEURODEGENERATION (2011)
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
Han-Xiang Deng et al.
NATURE (2011)
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
Merit Cudkowicz et al.
NATURE MEDICINE (2011)
Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1G93A mice model
Marcelo R. Vargas et al.
NEUROBIOLOGY OF DISEASE (2011)
Bcl2-A1 interacts with pro-caspase-3: Implications for amyotrophic lateral sclerosis
Ciro Iaccarino et al.
NEUROBIOLOGY OF DISEASE (2011)
Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis Examining a more efficient trial design
R. G. Miller et al.
NEUROLOGY (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Cao Huang et al.
PLOS GENETICS (2011)
Upregulation of Bax protein and increased DNA degradation in ALS spinal cord motor neurons
T. Ekegren et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
Mitochondrial Respiratory Chain Dysfunction in Muscle From Patients With Amyotrophic Lateral Sclerosis
Veronica Crugnola et al.
ARCHIVES OF NEUROLOGY (2010)
Mitochondria, oxidative metabolism and cell death in stroke
Neil R. Sims et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Extensive FUS-Immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions
Eric J. Huang et al.
BRAIN PATHOLOGY (2010)
Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity
Alberto Ferri et al.
HUMAN MOLECULAR GENETICS (2010)
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
Steve Pedrini et al.
HUMAN MOLECULAR GENETICS (2010)
Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis
Nichole A. Reyes et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
Kuen-Jer Tsai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
Ya-Fei Xu et al.
JOURNAL OF NEUROSCIENCE (2010)
Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
Brian D. Freibaum et al.
JOURNAL OF PROTEOME RESEARCH (2010)
Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
Adrian Israelson et al.
NEURON (2010)
Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
Jane O. Johnson et al.
NEURON (2010)
ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
Quan Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
Xiu Shan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Targeting post-mitochondrial effectors of apoptosis for neuroprotection
Lorenzo Galluzzi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS)
Kathryn Volkening et al.
BRAIN RESEARCH (2009)
The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice
Lee J. Martin et al.
EXPERIMENTAL NEUROLOGY (2009)
Recruitment of mitochondria into apoptotic signaling correlates with the presence of inclusions formed by amyotrophic lateral sclerosis-associated SOD1 mutations
Kai Y. Soo et al.
JOURNAL OF NEUROCHEMISTRY (2009)
The Human G93A-Superoxide Dismutase-1 Mutation, Mitochondrial Glutathione and Apoptotic Cell Death
H. Muyderman et al.
NEUROCHEMICAL RESEARCH (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Complex I and energy thresholds in the brain
Rashmi U. Pathak et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
ALS and FTLD: two faces of TDP-43 proteinopathy
R. M. Liscic et al.
EUROPEAN JOURNAL OF NEUROLOGY (2008)
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
Emanuele Buratti et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Deleterious role of superoxide dismutase in the mitochondrial intermembrane space
Gundars Goldsteins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TDP-43 Overexpression Enhances Exon 7 Inclusion during the Survival of Motor Neuron Pre-mRNA Splicing
Jayarama Krishnan Bose et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
I. -Fan Wang et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Mitochondrial dysfunction in S0D1G93A-bearing astrocytes promotes motor neuron degeneration:: Prevention by mitochondrial-targeted antioxidants
Patricia Cassina et al.
JOURNAL OF NEUROSCIENCE (2008)
Motor neuron disease - The curious ways of ALS
Magdalini Polymenidou et al.
NATURE (2008)
Mitochondrial fragmentation in neurodegeneration
Andrew B. Knott et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Mutant SOD1 from spinal cord of G93A rats is destabilized and binds to inner mitochondrial membrane
Toni Ahtoniemi et al.
NEUROBIOLOGY OF DISEASE (2008)
Selective assoction of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
Christine Vande Velde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
Felix Geser et al.
ACTA NEUROPATHOLOGICA (2008)
Mitochondrial alterations in dorsal root ganglion cells in sporadic amyotrophic lateral sclerosis
Shoichi Sasaki et al.
ACTA NEUROPATHOLOGICA (2007)
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial
Paul H. Gordon et al.
LANCET NEUROLOGY (2007)
Mitochondrial glutathione protects against cell death induced by oxidative and nitrative stress in astrocytes
Hakan Muyderman et al.
JOURNAL OF NEUROCHEMISTRY (2007)
TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease
Linda K. Kwong et al.
ACTA NEUROPATHOLOGICA (2007)
The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis
C. Hetz et al.
CELL DEATH AND DIFFERENTIATION (2007)
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
Ian R. A. Mackenzie et al.
ANNALS OF NEUROLOGY (2007)
Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis
Shoichi Sasaki et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Transgenic mouse models of amyotrophic lateral sclerosis
Jean-Pierre Julien et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
A century-old debate on protein aggregation and neurodegeneration enters the clinic
Peter T. Lansbury et al.
NATURE (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
Alberto Ferri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice
M Damiano et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice - A model of familial amyotrophic lateral sclerosis
HF Poon et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells
M Rizzardini et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2005)
Glutaredoxin:: Role in reversible protein S-glutathionylation and regulation of redox signal transduction and protein translocation
MD Shelton et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice
IG Kirkinezos et al.
JOURNAL OF NEUROSCIENCE (2005)
S-glutathionylation:: from redox regulation of protein functions to human diseases
D Giustarini et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2004)
Cu/Zn-superoxide dismutase (GLY93→ALA) mutation alters AMPA receptor subunit expression and function and potentiates kainate-mediated toxicity in motor neurons in culture
A Spalloni et al.
NEUROBIOLOGY OF DISEASE (2004)
Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
P Klivenyi et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Glutathione monoethyl ester provides neuroprotection in a rat model of stroke
MF Anderson et al.
NEUROSCIENCE LETTERS (2004)
Mitochondrial glutathione: A modulator of brain cell death
NR Sims et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2004)
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
P Pasinelli et al.
NEURON (2004)
Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis
J Karlsson et al.
JOURNAL OF NEUROSURGERY (2004)
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
AL Nishimura et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials
V Meininger et al.
AMYOTROPHIC LATERAL SCLEROSIS (2004)
Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model
M Tateno et al.
HUMAN MOLECULAR GENETICS (2004)
Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
S Sasaki et al.
ACTA NEUROPATHOLOGICA (2004)
A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis
ME Cudkowicz et al.
NEUROLOGY (2003)
ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes
CMJ Higgins et al.
BMC NEUROSCIENCE (2003)
Mitochondrial control of neuron death and its role in neurodegenerative disorders
J Jordán et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2003)
Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid
M Rizzardini et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α):: Transcriptional coactivator and metabolic regulator
P Puigserver et al.
ENDOCRINE REVIEWS (2003)
Mitochondrial DNA from platelets of sporadic ALS patients restores normal respiratory functions in ρ0 cells
CD Gajewski et al.
EXPERIMENTAL NEUROLOGY (2003)
Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
CW Jung et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Mitochondrial respiratory chain function in skeletal muscle of ALS patients
A Echaniz-Laguna et al.
ANNALS OF NEUROLOGY (2002)
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
M Mattiazzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS
C Guégan et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2002)
Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis
FM Menzies et al.
BRAIN (2002)
Oxidatively modified proteins in aging and disease
MF Beal
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival
RG Liu et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Ultrastructural changes of mitochondria in the skeletal muscle of patients with amyotrophic lateral sclerosis
MJ Chung et al.
ULTRASTRUCTURAL PATHOLOGY (2002)
Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily
D Sheehan et al.
BIOCHEMICAL JOURNAL (2001)
Superoxide dismutase and the death of motoneurons in ALS
JS Beckman et al.
TRENDS IN NEUROSCIENCES (2001)
Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity
C Bendotti et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2001)
Immunosuppressant FK506 does not exert beneficial effects in symptomatic G93A superoxide dismutase-1 transgenic mice
JMH Anneser et al.
NEUROREPORT (2001)
Intrathecal cyclosporin prolongs survival of late-stage ALS mice
M Keep et al.
BRAIN RESEARCH (2001)
Caspase-1 and-3 are Sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
P Pasinelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Metabolism and functions of glutathione in brain
R Dringen
PROGRESS IN NEUROBIOLOGY (2000)
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
MW Li et al.
SCIENCE (2000)