相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states
T. Yoshida et al.
BRITISH JOURNAL OF CANCER (2014)
Microtubules and actin crosstalk in cell migration and division
Tara Kafiyeh Akhshi et al.
CYTOSKELETON (2014)
Molecular mechanisms of epithelial-mesenchymal transition
Samy Lamouille et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities
R. A. Patel et al.
ONCOGENE (2014)
RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model
F. L. Byrne et al.
ONCOGENE (2014)
Rho-kinase: regulation, (dys) function, and inhibition
Ehsan Amin et al.
BIOLOGICAL CHEMISTRY (2013)
THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: ENZYMES
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: G PROTEIN-COUPLED RECEPTORS
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Angie Molina et al.
CANCER RESEARCH (2013)
A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Justine R. Stehn et al.
CANCER RESEARCH (2013)
Partial depletion of gamma-actin suppresses microtubule dynamics
Sela T. Po'uha et al.
CYTOSKELETON (2013)
Focal adhesion kinase overexpression: Correlation with lymph node metastasis and shorter survival in oral squamous cell carcinoma
Juan Carlos de Vicente et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2013)
New insights into the regulation and cellular functions of the ARP2/3 complex
Jeremy D. Rotty et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Implications of Rho GTPase signaling in glioma cell invasion and tumor progression
Shannon Patricia Fortin Ensign et al.
FRONTIERS IN ONCOLOGY (2013)
Eribulin mesylate: A novel halichondrin B analogue for the treatment of metastatic breast cancer
Ali McBride et al.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2012)
Rho family GTPases
Alan Hall
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
A role for microtubules in endothelial cell protrusion in three-dimensional matrices
Gabriel G. Martins et al.
BIOLOGY OF THE CELL (2012)
Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells
Masato Eitaki et al.
BMC CANCER (2012)
Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth
Renaud Prudent et al.
CANCER RESEARCH (2012)
Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy
Nicola Rath et al.
EMBO REPORTS (2012)
WAVE2 Protein Complex Coupled to Membrane and Microtubules
Kazuhide Takahashi
JOURNAL OF ONCOLOGY (2012)
Advancements in the Treatment of Metastatic Breast Cancer (MBC): The Role of Ixabepilone
Massimo Cristofanilli
JOURNAL OF ONCOLOGY (2012)
Treating metastatic cancer with nanotechnology
Avi Schroeder et al.
NATURE REVIEWS CANCER (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Vimentin in cancer and its potential as a molecular target for cancer therapy
Arun Satelli et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer
Jone Trovik et al.
CLINICAL CANCER RESEARCH (2011)
Stathmin: a protein with many tasks. New biomarker and potential target in cancer
Barbara Belletti et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
γ-Actin regulates cell migration and modulates the ROCK signaling pathway
Michael S. Y. Shum et al.
FASEB JOURNAL (2011)
The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs
Robert R. Langley et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
OPINION Mitosis is not a key target of microtubule agents in patient tumors
Edina Komlodi-Pasztor et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility
J. G. Lees et al.
ONCOGENE (2011)
Regulation of cell migration by dynamic microtubules
Irina Kaverina et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2011)
Common themes in centriole and centrosome movements
Sue Vaughan et al.
TRENDS IN CELL BIOLOGY (2011)
Nestin in gastrointestinal and other cancers: Effects on cells and tumor angiogenesis
Toshiyuki Ishiwata et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Filamin A is required for vimentin-mediated cell adhesion and spreading
Hugh Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Hypoxia, inflammation, and the tumor microenvironment in metastatic disease
Elizabeth C. Finger et al.
CANCER AND METASTASIS REVIEWS (2010)
βIII-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non-Small Cell Lung Cancer
Joshua A. McCarroll et al.
CANCER RESEARCH (2010)
The expression of CFL1 and N-WASP in esophageal squamous cell carcinoma and its correlation with clinicopathological features
Wei-Sen Wang et al.
DISEASES OF THE ESOPHAGUS (2010)
Regulation of cell adhesion to collagen via β1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon
Hugh Kim et al.
EXPERIMENTAL CELL RESEARCH (2010)
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells
Rebecca W. Scott et al.
JOURNAL OF CELL BIOLOGY (2010)
Expression of Cortactin Correlates with a Poor Prognosis in Patients with Stages II-III Colorectal Adenocarcinoma
Jian-hua Cai et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2010)
VEGF and Cortactin Expression Are Independent Predictors of Tumor Recurrence Following Curative Resection of Gastric Cancer
Xin Wang et al.
JOURNAL OF SURGICAL ONCOLOGY (2010)
Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression
Xu-Zhi Xu et al.
MODERN PATHOLOGY (2010)
Metronomic chemotherapy: new rationale for new directions
Eddy Pasquier et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
Microtubule-binding agents: a dynamic field of cancer therapeutics
Charles Dumontet et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs
S. T. Po'uha et al.
ONCOGENE (2010)
Overexpression of Cortactin Increases Invasion Potential in Oral Squamous Cell Carcinoma
Shin-ichi Yamada et al.
PATHOLOGY & ONCOLOGY RESEARCH (2010)
Tropomyosin isoform modulation of focal adhesion structure and cell migration
Cuc T. T. Bach et al.
CELL ADHESION & MIGRATION (2010)
Microtubules and resistance to tubulin-binding agents
Maria Kavallaris
NATURE REVIEWS CANCER (2010)
Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Dolores Di Vizio et al.
CANCER RESEARCH (2009)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
Expression of survivin and cortactin in colorectal adenocarcinoma: Association with clinicopathological parameters
Ying-Yu Lee et al.
DISEASE MARKERS (2009)
Cortactin, fascin, and survivin expression associated with clinicopathological parameters in esophageal squamous cell carcinoma
K. -F. Hsu et al.
DISEASES OF THE ESOPHAGUS (2009)
Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion
Tan Zhang et al.
JOURNAL OF CELL SCIENCE (2009)
High expression of stathmin protein predicts a fulminant course in medulloblastoma Clinical article
Meng-Fai Kuo et al.
JOURNAL OF NEUROSURGERY-PEDIATRICS (2009)
Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas
J. P. Rodrigo et al.
JOURNAL OF PATHOLOGY (2009)
Tropomyosin Isoform Expression Regulates the Transition of Adhesions To Determine Cell Speed and Direction
Cuc T. T. Bach et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
8p22 MTUS1 Gene Product ATIP3 Is a Novel Anti-Mitotic Protein Underexpressed in Invasive Breast Carcinoma of Poor Prognosis
Sylvie Rodrigues-Ferreira et al.
PLOS ONE (2009)
Rho family GTPases and their regulators in lymphocytes
Victor L. J. Tybulewicz et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Prognostic significance of stathmin expression in correlation with metastasis and clinicopathological characteristics in human ovarian carcinoma
San-Hua Wei et al.
ACTA HISTOCHEMICA (2008)
Cortactin expression predicts poor survival in laryngeal carcinoma
J. H. Gibcus et al.
BRITISH JOURNAL OF CANCER (2008)
Tubulin-Targeted Drug Action: Functional Significance of Class II and Class IVb β-Tubulin in Vinca Alkaloid Sensitivity
Pei Pei Gan et al.
CANCER RESEARCH (2008)
Asymmetric focal adhesion disassembly in motile cells
Joshua A. Broussard et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Contractile forces in tumor cell migration
Claudia Tanja Mierke et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2008)
Intermediate filament protein synemin contributes to the migratory properties of astrocytoma cells by influencing the dynamics of the actin cytoskeleton
Yihang Pan et al.
FASEB JOURNAL (2008)
Rho GTPases in cancer cell biology
Francisco M. Vega et al.
FEBS LETTERS (2008)
Overexpression of FMNL2 is closely related to metastasis of colorectal cancer
Xi-Ling Zhu et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2008)
Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of slingshot or LIM kinase
Yuji Horita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility
Yang Lim et al.
JOURNAL OF CELL BIOLOGY (2008)
Cell motility through plasma membrane blebbing
Oliver T. Fackler et al.
JOURNAL OF CELL BIOLOGY (2008)
Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors
Petra Ross-Macdonald et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Blebs lead the way: how to migrate without lamellipodia
Guillaume Charras et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Tropomyosin-based regulation of the actin cytoskeleton in time and space
Peter Gunning et al.
PHYSIOLOGICAL REVIEWS (2008)
N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer
Tracey A. Martin et al.
CLINICAL & EXPERIMENTAL METASTASIS (2008)
The abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin Contractility and regulate focal adhesion dynamics upon adhesion to fibronectin
Justin G. Peacock et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Class III β-tubulin mediates sensitivity to chemotherapeutic drugs in non-small cell lung cancer
Pei Pei Gan et al.
CANCER RESEARCH (2007)
Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma
Keiichi Iwaya et al.
CANCER SCIENCE (2007)
Muscle intermediate filaments and their links to membranes and membranous organelles
Yassemi Capetanaki et al.
EXPERIMENTAL CELL RESEARCH (2007)
Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments
Ram K. Sihag et al.
EXPERIMENTAL CELL RESEARCH (2007)
Regulation of the actin cytoskeleton in cancer cell migration and invasion
Hideki Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Coexpression of Arp2 and WAVE2 predicts poor outcome in invasive breast carcinoma
Keiichi Iwaya et al.
MODERN PATHOLOGY (2007)
Lim kinases, regulators of actin dynamics
Ora Bernard
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Proteomic analysis of isolated membrane fractions from superinvasive cancer cells
Paul Dowling et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2007)
The cofilin pathway in breast cancer invasion and metastasis
Weigang Wang et al.
NATURE REVIEWS CANCER (2007)
Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance
Man-Li Luo et al.
CANCER RESEARCH (2006)
Mechanisms of invasion and metastasis in human neuroblastoma
Tasnim Ara et al.
CANCER AND METASTASIS REVIEWS (2006)
Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis
Ghassan Mouneimne et al.
CURRENT BIOLOGY (2006)
Alterations in γ-actin and tubulin-targeted drug resistance in childhood leukemia
Nicole M. Verrills et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
Jeffrey B. Wyckoff et al.
CURRENT BIOLOGY (2006)
Tumor metastasis: mechanistic insights and clinical challenges
Patricia S. Steeg
NATURE MEDICINE (2006)
Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration
Stephanie L. Gupton et al.
CELL (2006)
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
W Wang et al.
JOURNAL OF CELL BIOLOGY (2006)
Differential protein expression profiling by iTRAO-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype
VG Keshamouni et al.
JOURNAL OF PROTEOME RESEARCH (2006)
Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung
S Semba et al.
CLINICAL CANCER RESEARCH (2006)
Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis
D Turhani et al.
ELECTROPHORESIS (2006)
Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia -: An in vivo study
NM Verrills et al.
PROTEOMICS (2006)
The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors
F Di Modugno et al.
CLINICAL CANCER RESEARCH (2006)
LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system
R Bagheri-Yarmand et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Resensitization of breast cancer cells to anoikis by Tropomyosin-1: role of Rho kinase-dependent cytoskeleton and adhesion
S Bharadwaj et al.
ONCOGENE (2005)
Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the α6β4 integrin
SO Yoon et al.
CANCER RESEARCH (2005)
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
KL Rossman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
G Baldassarre et al.
CANCER CELL (2005)
Microtubules as a target for anticancer drugs
MA Jordan et al.
NATURE REVIEWS CANCER (2004)
Integrins in mechanotransduction
A Katsumi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Stathmin-tubulin interaction gradients in motile and mitotic cells
P Niethammer et al.
SCIENCE (2004)
Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis
XS Hao et al.
CANCER (2004)
Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma
CE Schmalbach et al.
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2004)
Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1
T Wittmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
YL Yu et al.
NATURE MEDICINE (2004)
Multiple connections link FAK to cell motility and invasion
DD Schlaepfer et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2004)
The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis
C Khanna et al.
NATURE MEDICINE (2004)
Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma
M Chuma et al.
JOURNAL OF HEPATOLOGY (2004)
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
G Mouneimne et al.
JOURNAL OF CELL BIOLOGY (2004)
Intermediate filaments mediate cytoskeletal crosstalk
L Chang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer
T Kamai et al.
CLINICAL CANCER RESEARCH (2004)
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
WG Wang et al.
CANCER RESEARCH (2004)
Control of axonal branching and synapse formation by focal adhesion kinase
B Rico et al.
NATURE NEUROSCIENCE (2004)
The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress
D Tsuruta et al.
JOURNAL OF CELL SCIENCE (2003)
Cell migration: Integrating signals from front to back
AJ Ridley et al.
SCIENCE (2003)
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
E Sahai et al.
NATURE CELL BIOLOGY (2003)
Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
A Horiuchi et al.
LABORATORY INVESTIGATION (2003)
Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro
N Cordes et al.
BRITISH JOURNAL OF CANCER (2003)
Cellular motility driven by assembly and disassembly of actin filaments
TD Pollard et al.
CELL (2003)
Characterization of RhoC expression in benign and malignant breast disease - A potential new marker for small breast carcinomas with metastatic ability
CG Kleer et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
The lamellipodium: where motility begins
JV Small et al.
TRENDS IN CELL BIOLOGY (2002)
Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray
R Yanagawa et al.
NEOPLASIA (2001)
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCζ
S Etienne-Manneville et al.
CELL (2001)
RhoA/Rho-associated kinase mediates fibroblast contractile force generation
HF Yee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Vertebrate tropomyosin: distribution, properties and function
SV Perry
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2001)