相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes
M. Mezler et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Multiple Defects in Energy Metabolism in Alzheimers Disease
I. L. Ferreira et al.
CURRENT DRUG TARGETS (2012)
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils
Jan Bieschke et al.
NATURE CHEMICAL BIOLOGY (2012)
AD synapses contain abundant Aβ monomer and multiple soluble oligomers, including a 56-kDa assembly
Sophie Sokolow et al.
NEUROBIOLOGY OF AGING (2012)
Magnetic resonance imaging and neuropsychological results from a trial of memantine in Alzheimer's disease
Michael W. Weiner et al.
ALZHEIMERS & DEMENTIA (2011)
Prolonged exposure of cortical neurons to oligomeric amyloid-beta impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate
Yan He et al.
ASN NEURO (2011)
Behavioural and cellular effects of exogenous amyloid-β peptides in rodents
Caroline Chambon et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine
Csaba Nyakas et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
Claire Thornton et al.
BIOCHEMICAL JOURNAL (2011)
Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model
Teresa Ponce-Lopez et al.
BRAIN RESEARCH (2011)
New updated GRAC Fifth Edition with searchable online version Launch of new portal Guide to Pharmacology in association with NC-IUPHAR Transporter-Themed Issue
Steve Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Amyloid β peptide oligomers directly activate NMDA receptors
Laura Texido et al.
CELL CALCIUM (2011)
Aβ Oligomer-Induced Synapse Degeneration in Alzheimer's Disease
Kyle C. Wilcox et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2011)
Neuronal Death Induced by Nanomolar Amyloid β Is Mediated by Primary Phagocytosis of Neurons by Microglia
Urte Neniskyte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein
Andrew E. Barry et al.
JOURNAL OF NEUROSCIENCE (2011)
Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors
Shaomin Li et al.
JOURNAL OF NEUROSCIENCE (2011)
Protection against Aβ-mediated rapid disruption of synaptic plasticity and memory by memantine
Igor Klyubin et al.
NEUROBIOLOGY OF AGING (2011)
The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease
Sergio T. Ferreira et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2011)
Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices
Gerhard Rammes et al.
NEUROPHARMACOLOGY (2011)
Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer's disease
Mohammed Filali et al.
NEUROPHARMACOLOGY (2011)
Calcium Ions Promote Formation of Amyloid β-Peptide (1-40) Oligomers Causally Implicated in Neuronal Toxicity of Alzheimer's Disease
Anna Itkin et al.
PLOS ONE (2011)
Synapses, NMDA receptor activity and neuronal A beta production in Alzheimer's disease
Karim Bordji et al.
REVIEWS IN THE NEUROSCIENCES (2011)
Memantine Improves Cognition and Reduces Alzheimer's-Like Neuropathology in Transgenic Mice
Hilda Martinez-Coria et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Higher Soluble Amyloid β Concentration in Frontal Cortex of Young Adults than in Normal Elderly or Alzheimer's Disease
Zoe van Helmond et al.
BRAIN PATHOLOGY (2010)
Inhibition of calpain prevents NMDA-induced cell death and β-amyloid-induced synaptic dysfunction in hippocampal slice cultures
V. Nimmrich et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors
Elena Alberdi et al.
CELL CALCIUM (2010)
Folic Acid Potentiates the Effect of Memantine on Spatial Learning and Neuronal Protection in an Alzheimer's Disease Transgenic Model
Ta-Fu Chen et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Amyloid-beta Induces Caspase-Dependent Loss of PSD-95 and Synaptophysin Through NMDA Receptors
Jinping Liu et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Calcium Signaling and Amyloid Toxicity in Alzheimer Disease
Angelo Demuro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer's toxic amyloid-β peptide oligomers
Helena Decker et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Amyloid-β Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3β in Primary Cultured Hippocampal Neurons
Helena Decker et al.
JOURNAL OF NEUROSCIENCE (2010)
Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-β Production
Karim Bordji et al.
JOURNAL OF NEUROSCIENCE (2010)
Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses
Peng Xia et al.
JOURNAL OF NEUROSCIENCE (2010)
A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
Takami Tomiyama et al.
JOURNAL OF NEUROSCIENCE (2010)
Memantine Lowers Amyloid-beta Peptide Levels in Neuronal Cultures and in APP/PS1 Transgenic Mice
George M. Alley et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Amyloid beta from axons and dendrites reduces local spine number and plasticity
Wei Wei et al.
NATURE NEUROSCIENCE (2010)
Alzheimer's disease: strategies for disease modification
Martin Citron
NATURE REVIEWS DRUG DISCOVERY (2010)
Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5
Marianne Renner et al.
NEURON (2010)
Memantine treatment decreases levels of secreted Alzheimer's amyloid precursor protein (APP) and amyloid beta (Aβ) peptide in the human neuroblastoma cells
Balmiki Ray et al.
NEUROSCIENCE LETTERS (2010)
Brain amyloid beta protein and memory disruption in Alzheimer's disease
Weiming Xia
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2010)
Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides
Dagmar Schlenzig et al.
BIOCHEMISTRY (2009)
Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production
Sarah E. Hoey et al.
JOURNAL OF NEUROSCIENCE (2009)
A Role for Synaptic Zinc in Activity-Dependent Aβ Oligomer Formation and Accumulation at Excitatory Synapses
Atul Deshpande et al.
JOURNAL OF NEUROSCIENCE (2009)
β-Amyloid Monomers Are Neuroprotective
Maria Laura Giuffrida et al.
JOURNAL OF NEUROSCIENCE (2009)
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
Shu-ichi Okamoto et al.
NATURE MEDICINE (2009)
Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
Efrat Abramov et al.
NATURE NEUROSCIENCE (2009)
Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice
I. Dewachter et al.
NEUROBIOLOGY OF AGING (2009)
Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
Shaomin Li et al.
NEURON (2009)
EFFECTS OF MEMANTINE ON SOLUBLE Aβ25-35-INDUCED CHANGES IN PEPTIDERGIC AND GLIAL CELLS IN ALZHEIMER'S DISEASE MODEL RAT BRAIN REGIONS
M. Arif et al.
NEUROSCIENCE (2009)
GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo
Neng-Wei Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Increased expression of PAD2 after repeated intracerebroventricular infusions of soluble Aβ25-35 in the Alzheimer's disease model rat brain: Effect of memantine
Mohammad Arif et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2009)
Long-term course and effectiveness of combination therapy in Alzheimer disease
Alireza Atri et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2008)
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
Dennis J. Selkoe
BEHAVIOURAL BRAIN RESEARCH (2008)
Therapeutically relevant plasma concentrations of memantine produce significant L-N-methyl-D-aspartate receptor occupation and do not impair learning in rats
Lorenzo More et al.
BEHAVIOURAL PHARMACOLOGY (2008)
Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease
C. -X. Gong et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation
M. S. Song et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
β-amyloid and glutamate receptors
Laura Gasparini et al.
EXPERIMENTAL NEUROLOGY (2008)
Amyloid beta peptides and glutamatergic synaptic dysregulation
Kodeeswaran Parameshwaran et al.
EXPERIMENTAL NEUROLOGY (2008)
Amyloid beta oligomers induce impairment of neuronal insulin receptors
Wei-Qin Zhao et al.
FASEB JOURNAL (2008)
Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons
Phullara B. Shelat et al.
JOURNAL OF NEUROCHEMISTRY (2008)
NMDA- and β-Amyloid1-42-Induced Neurotoxicity Is Attenuated in Serine Racemase Knock-Out Mice
Ran Inoue et al.
JOURNAL OF NEUROSCIENCE (2008)
Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus
Daniela Puzzo et al.
JOURNAL OF NEUROSCIENCE (2008)
Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging
Henrieta Scholtzova et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Amyloid β-peptide activates nuclear factor-κB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells
E. M. Kawamoto et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Aβ1-42 modulation of Akt phosphorylation via α7 nAChR and NMDA receptors
Jonathan J. Abbott et al.
NEUROBIOLOGY OF AGING (2008)
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
Fernanda G. De Felice et al.
NEUROBIOLOGY OF AGING (2008)
Calcium dysregulation in Alzheimer's disease
Lukasz Bojarski et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
Endocytosis is required for synaptic activity-dependent release of amyloid-β in vivo
John R. Cirrito et al.
NEURON (2008)
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating
King-Ho Cheung et al.
NEURON (2008)
Memantine:: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutarnatergic system -: too little activation is bad, too much is even worse
Chris G. Parsons et al.
NEUROPHARMACOLOGY (2007)
β-amyloid modulation of synaptic transmission and plasticity
Deepa V. Venkitaramani et al.
JOURNAL OF NEUROSCIENCE (2007)
β-amyloid pathology in the entorhinal cortex of rats induces memory deficits:: Implications for Alzheimer's disease
E. Sipos et al.
NEUROSCIENCE (2007)
High content screen microscopy analysis of Ap1-42-induced neurite outgrowth reduction in rat primary cortical neurons:: Neuroprotective effects of α7 neuronal nicotinic acetylcholine receptor ligands
Min Hu et al.
BRAIN RESEARCH (2007)
Toxicity of β-amyloid in HEK293 cells expressing NR1/NR2A or NR1/NR2B N-methyl-D-aspartate receptor subunits
A. Dorningues et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
Fernanda G. De Felice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
Ganesh M. Shankar et al.
JOURNAL OF NEUROSCIENCE (2007)
Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
Pascale N. Lacor et al.
JOURNAL OF NEUROSCIENCE (2007)
Mitoenergetic failure in Alzheimer disease
Mordhwaj S. Parihar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Monoclonal antibodies that target pathological assemblies of A beta
Mary P. Lambert et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Analysis of the effect of memantine in reducing the worsening of clinical symptoms in patients with moderate to severe Alzheimer's disease
David Wilkinson et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2007)
Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases
Sergio T. Ferreira et al.
IUBMB LIFE (2007)
AMPAR removal underlies Aβ-induced synaptic depression and dendritic spine loss
Helen Hsieh et al.
NEURON (2006)
Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-β oligomers
Matthew Townsend et al.
ANNALS OF NEUROLOGY (2006)
Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat
S. Rosi et al.
NEUROSCIENCE (2006)
Cognitive dysfunction induced by sequential injection of amyloid-β and ibotenate into the bilateral hippocampus;: protection by memantine and MK-801
Shizuo Nakamura et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane
Phillip R. Zoladz et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2006)
Memantine treatment in mild to moderate Alzheimer disease: A 24-week randomized, controlled trial
Elaine R. Peskind et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2006)
Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease
Sara L. Kirvell et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity
Christiane Volbracht et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice
C Unger et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Altered synaptic function in Alzheimer's disease
Karen F. S. Bell et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model
D Van Dam et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2006)
3-nitropropionic acid toxicity in hippocampus: Protection through N-methyl-D-aspartate receptor antagonism
David A. Karanian et al.
HIPPOCAMPUS (2006)
Tau therapeutic strategies for the treatment of Alzheimer's disease
Ian Churcher
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on memantine
Gary L. Wenk et al.
BEHAVIOURAL PHARMACOLOGY (2006)
Comparison of donepezil and memantine for protective effect against amyloid-beta(1-42) toxicity in rat septal neurons
M Kimura et al.
NEUROSCIENCE LETTERS (2005)
Mechanism of impairment of long-term potentiation by amyloid β is independent of NMDA receptors or voltage-dependent calcium channels in hippocampal CA1 pyramidal neurons
I Nomura et al.
NEUROSCIENCE LETTERS (2005)
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
JR Cirrito et al.
NEURON (2005)
β-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor
QW Wang et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Soluble β-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses
F Roselli et al.
JOURNAL OF NEUROSCIENCE (2005)
Divergent effects of Aβ1-42 on ionotropic glutamate receptor-mediated responses in CA1 neurons in vivo
V Szegedi et al.
BRAIN RESEARCH (2005)
Globular amyloid β-peptide1-42 oligomer -: a homogenous and stable neuropathological protein in Alzheimer's disease
S Barghorn et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Regulation of NMDA receptor trafficking by amyloid-β
EM Snyder et al.
NATURE NEUROSCIENCE (2005)
Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats
K Yamada et al.
BEHAVIOURAL BRAIN RESEARCH (2005)
β-Amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors
AM Floden et al.
JOURNAL OF NEUROSCIENCE (2005)
Soluble Arctic amyloid β protein inhibits hippocampal long-term potentiation in vivo
I Klyubin et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
β-Amyloid25-35 inhibits glutamate uptake in cultured neurons and astrocytes:: modulation of uptake as a survival mechanism
P Fernández-Tomé et al.
NEUROBIOLOGY OF DISEASE (2004)
The role of c-Jun N-terminal kinase in the Aβ-mediated impairment of LTP and regulation of synaptic transmission in the hippocampus
DA Costello et al.
NEUROPHARMACOLOGY (2004)
Block of long-term potentiation by naturally secreted and synthetic amyloid β-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
QW Wang et al.
JOURNAL OF NEUROSCIENCE (2004)
Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil - A randomized controlled trial
PN Tariot et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Amyloid β-protein induced electrophysiological changes are dependent on aggregation state:: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation
CP Ye et al.
NEUROSCIENCE LETTERS (2004)
Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyte-derived macrophages: implications for the pathogenesis of Alzheimer's disease
HG Xiong et al.
NEUROBIOLOGY OF AGING (2004)
Enhancement of NMDA responses by β-amyloid peptides in the hippocampus in vivo
Z Molnár et al.
NEUROREPORT (2004)
β-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
QW Wang et al.
JOURNAL OF NEUROSCIENCE (2004)
Amyloid β prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation
DY Zhao et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease
R Minkeviciene et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Neurodegenerative diseases and oxidative stress
J Emerit et al.
BIOMEDICINE & PHARMACOTHERAPY (2004)
Glutamatergic systems in Alzheimer's disease
PT Francis
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2003)
The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence
W Danysz et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2003)
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
W Noble et al.
NEURON (2003)
Amyloid precursor protein-processing products affect mononuclear phagocyte activation:: pathways for sAPP- and Aβ-mediated neurotoxicity
T Ikezu et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Synaptic plasticity in animal models of early Alzheimer's disease
MJ Rowan et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2003)
NMDA receptor regulation by amyloid-β does not account for its inhibition of LTP in rat hippocampus
CR Raymond et al.
BRAIN RESEARCH (2003)
Memantine in moderate-to-severe Alzheimer's disease
B Reisberg et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Hyperhomocysteinemia as a new risk factor for brain shrinkage in patients with alcoholism
S Bleich et al.
NEUROSCIENCE LETTERS (2003)
The glutamatergic system and Alzheimer's disease - Therapeutic implications
DA Butterfield et al.
CNS DRUGS (2003)
Amyloid beta protein enhances the clearance of extracellular L-glutamate by cultured rat cortical astrocytes
K Abe et al.
NEUROSCIENCE RESEARCH (2003)
Neuroprotection by memantine against neurodegeneration induced by β-amyloid(1-40)
JJ Miguel-Hidalgo et al.
BRAIN RESEARCH (2002)
A novel β-sheet breaker, RS-0406, reverses amyloid β-induced cytotoxicity and impairment of long-term potentiation in vitro
Y Nakagami et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
β-amyloid enhances glial glutamate uptake activity and attenuates synaptic efficacy
Y Ikegaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Alzheimer amyloid β-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus
QS Chen et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Glutamate exacerbates amyloid β1-42-induced impairment of long-term potentiation in rat hippocampal slices
Y Nakagami et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2002)
Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
HW Wang et al.
BRAIN RESEARCH (2002)
Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists
X Bi et al.
NEUROSCIENCE (2002)
Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
SW Barger et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction
H Katagiri et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain:: the role of Aβ1-42
CM Lauderback et al.
JOURNAL OF NEUROCHEMISTRY (2001)
GlutamateNMDA receptor NR1 subunit mRNA expression in Alzheimer's disease
MR Hynd et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Glutamate transporters in neurologic disease
NJ Maragakis et al.
ARCHIVES OF NEUROLOGY (2001)
Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro
JK Parks et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Mitochondria and calcium: from cell signalling to cell death
MR Duchen
JOURNAL OF PHYSIOLOGY-LONDON (2000)
β-Amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis
T Harkany et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice
E Masliah et al.
EXPERIMENTAL NEUROLOGY (2000)
Neuroprotective and symptomatological action of memantine relevant for alzheimer's disease - a unified glutamatergic hypothesis on the mechanism of action
Wojciech Danysz et al.
NEUROTOXICITY RESEARCH (2000)
The cytotoxicity of chronic neuroinflammation upon basal forebrain cholinergic neurons of rats can be attenuated by glutamatergic antagonism or cyclooxygenase-2 inhibition
LB Willard et al.
EXPERIMENTAL BRAIN RESEARCH (2000)