期刊
BRITISH JOURNAL OF NUTRITION
卷 110, 期 11, 页码 2058-2068出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114513001426
关键词
Mediterranean diet; Pregnancy; Wheeze; Eczema; Infants
资金
- Instituto de Salud Carlos III [INMA G03/176, CB06/02/0041, FIS-FEDER 03/1615, 04/1509, 04/1112, 04/1931, 05/1079, 05/1052, 06/1213, 07/0314, 09/02647, FISS-PI042018, FISS-PI09/02311, FIS-PI06/0867, FIS-PS09/00090, FIS-PI041436, FIS-PI081151]
- Conselleria de Sanitat Generalitat Valenciana, Generalitat de Catalunya [CIRIT 1999SGR 00241]
- Obra social Cajastur, Universidad de Oviedo, Department of Health of the Basque Government [2005111093, 2009111069]
- Provincial Government of Gipuzkoa [DFG06/004, DFG08/001]
- European Union (EU) [EU FP6-2003-Food-3-A, EU FP7 ENV. 2007.1.2.2.2, 211250 Escape, EU FP7-2008-ENV-1.2.1.4 Envirogenomarkers, EU FP7-HEALTH-2009, EU FP7 ENV. 2008.1.2.1.6]
- Greek Ministry of Health (Program of Prevention of obesity and neurodevelopmental disorders in preschool children, in Heraklion district, Crete, Greece)
Maternal diet during pregnancy might influence the development of childhood allergic disorders. The aim of the present study was to evaluate the impact of Mediterranean diet (MD) adherence during pregnancy on wheeze and eczema in the first year of life in two population- based mother-child cohorts in Spain and Greece. We studied 1771 mother-newborn pairs from the Spanish multi-centre ` INMA' (INfancia y Medio Ambiente) study (Gipuzkoa, Sabadell and Valencia) and 745 pairs from the ` RHEA' study in Crete, Greece. The symptoms of wheeze and eczema were based on the criteria of the International Study of Asthma and Allergies in Childhood. Maternal diet during pregnancy was assessed by FFQ and MD adherence was evaluated through an a priori score. Multivariate log-binomial regression models were used to adjust for several confounders in each cohort and summary estimates were obtained by a meta-analysis. MD adherence was not associated with the risk of wheeze and eczema in any cohort, and similar results were identified in the meta-analysis approach. High meat intake (relative risk (RR) 1.22, 95% CI 1.00, 1.49) and 'processed' meat intake (RR 1.18, 95% CI 1.02, 1.37) during pregnancy were associated with an increased risk of wheeze in the first year of life, while a high intake of dairy products was significantly associated with a decreased risk of infantile wheeze (RR 0.83, 95% CI 0.72, 0.96). The results of the present study show that high meat intake during pregnancy may increase the risk of wheeze in the first year of life, while a high intake of dairy products may decrease it.
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