期刊
BRITISH JOURNAL OF NUTRITION
卷 109, 期 1, 页码 65-75出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114512000670
关键词
Gastro-intestinal tract; Digestion; Intra-uterine growth restriction; Piglets
资金
- Onderzoeksfonds
- College University Ghent
The digestive function of low birth weight (LBW) pigs post-weaning has been poorly studied. Therefore, newborns from eleven hyper-prolific sows were weighed, weaned at 27.2 d and fed a starter diet until sampling. Sampling was done between 18 and 28 d post-weaning. An LBW piglet (n 19) was defined as a piglet having a birth weight less than 1 kg and less than the lower quartile of litter birth weights. Normal birth weight (NBW) piglets (n 13) were having a birth weight close to the mean litter birth weight. For each piglet, eighty-eight variables were determined. Data were analysed with linear models with type of piglet and litter as predictors. A principal component analysis was performed to determine the most important discriminating variables. In the LBW pig, the development of the digestive tract post-weaning was delayed: lower small-intestinal weight: length ratio due to a thinner tela submucosa and tunica muscularis and a higher secretory capacity, both in the distal jejunum. These observations might be a consequence of lower circulating insulin-like growth factor-1 (IGF-1) concentrations (126 (SE 10.0) v. 158 (SE 12.0) ng/ml for LBW and NBW, respectively) and a lower density of IGF-1 receptors in the proximal small intestine. Additionally, the plasma antioxidant capacity was lower for the LBW pig. Taken together, in the LBW piglet, the normal gut maturation post-weaning was retarded and this did not seem to be related to the weaning transition as such.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据