期刊
BRITISH JOURNAL OF NUTRITION
卷 103, 期 6, 页码 907-912出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0007114509992480
关键词
Monounsaturated fat; Almonds; Inflammation; Haemostasis; Endothelial dysfunction; CHD
资金
- Center for Health and Nutrition Research at the University of California, Davis
- Almond Board of California, Fresno, CA
- Dr Russell Tracy, University of Vermont, Burlington, VT, USA
Frequent consumption of nuts lowers the risk of CHD. While lowering blood lipids is one of the mechanisms for cardioprotection, the present study sought to determine whether monounsaturated fat-rich almonds also influence other CHD risk factors such as inflammation and haemostasis. This was a randomised, controlled, crossover feeding study with twenty-five healthy adults (eleven men; fourteen women), age 22-53 years. Following a 2 week run-in phase (34 % energy from fat), subjects were assigned in random order to three diets for 4 weeks each: a heart-healthy control diet with no nuts (<30% energy from fat), low-almond diet and high-almond diet (10% or 20% isoenergetic replacement of control diet with almonds, respectively). Serum E-selectin was significantly lower on the high-almond diet compared with the control diet. E-selectin decreased as the percentage of energy from almonds increased (P<0.0001). C-reactive protein (CRP) was lower in both the almond diets compared with the control diet. A clear dose response was not observed for either E-selectin or CRP. There was no effect of diet on IL-6 or fibrinogen. Tissue plasminogen activator antigen was significantly lower on the control and high-almond diets compared with the low-almond diet, although the values were within normal range. In conclusion, consumption of almonds influenced a few but not all of the markers of inflammation and haemostasis. A clear dose response was not observed for any of the markers studied.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据