期刊
PLANT SIGNALING & BEHAVIOR
卷 4, 期 8, 页码 760-762出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/psb.4.8.9174
关键词
maize; epigenetics; histone modification; DNA methylation; small RNA; transcriptome; next-generation sequencing
资金
- National Institutes of Health [GM047850]
- National Science Foundation Plant Genome Program [DBI0421675]
- National Science Foundation
- Ministry of Science and Technology of China
- Beijing Commission of Science and Technology
- Yale University
Epigenetic modifications and small RNAs play an important role in gene regulation. Here, we discuss results of our Solexa/Illumina 1G sequencing-based survey of DNA methylation, activating and repressive histone modifications, small RNAs and mRNA in the maize genome. We analyze tissue-specific epigenetic patterns, discuss antagonistic relationships between repressive epigenetic marks and highlight synergistic relationships between activating histone modifications. We discuss our observation that small RNAs show a tissue-specific distribution in maize. Whereas 24-nucleotide long small interfering RNAs (siRNAs) accumulated preferentially in shoots, 21-nucleotide long micro RNAs (miRNAs) were the most abundant group in roots, which follows the transcript level of mop1. Furthermore, we discuss the possibility that a novel class of 22-nucleotide siRNAs might originate from long double-stranded RNAs in an RNA-dependent RNA polymerase (RdRP)-independent manner. This supports the intriguing possibility that maize possesses at least two distinct pathways to generate siRNAs, one of which relies on RdRP and a second one that might be RdRP-independent.
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