期刊
BRITISH JOURNAL OF HAEMATOLOGY
卷 157, 期 4, 页码 413-425出版社
WILEY
DOI: 10.1111/j.1365-2141.2012.09107.x
关键词
myelofibrosis; stem cell transplant; splenectomy; JAK inhibitors
类别
资金
- Medical Research Council [G84/6443] Funding Source: Medline
- MRC [G84/6443] Funding Source: UKRI
- Medical Research Council [G84/6443] Funding Source: researchfish
Myelofibrosis (MF) is a heterogeneous disease for which long-term, effective medical therapeutic options are currently limited. The role of allogeneic haematopoietic stem cell transplant (AHSCT) in this population, many of whom are elderly, often provides a challenge with regard to the identification of suitable candidates, timing of transplantation in the disease course and choice of conditioning regimen. This review summarizes key findings from published data concerning AHSCT in MF and attempts to provide a state of the art approach to MF-AHSCT in 2012. In addition, we postulate on how the era of JAK inhibition might impact on transplantation for MF.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据