相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Antioxidants in Central Nervous System Diseases: Preclinical Promise and Translational Challenges
Chandrashekhar D. Kamat et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms
K. Gupta et al.
CELL DEATH AND DIFFERENTIATION (2012)
Modeling Brain Disease in a Dish: Really?
Maria C. Marchetto et al.
CELL STEM CELL (2012)
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
Adriana Sanchez-Danes et al.
EMBO MOLECULAR MEDICINE (2012)
Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis
Bi Song et al.
STEM CELL RESEARCH (2012)
Human-Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke-Damaged Brain
Koichi Oki et al.
STEM CELLS (2012)
CNS Peroxiredoxins and Their Regulation in Health and Disease
Karen F. S. Bell et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Regulation of Neuronal Oxidative and Nitrosative Stress by Endogenous Protective Pathways and Disease Processes
Giles E. Hardingham et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
The Human Brain in a Dish: The Promise of iPSC-Derived Neurons
Ricardo Dolmetsch et al.
CELL (2011)
Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells
O. Cordero-Llana et al.
CELL DEATH AND DIFFERENTIATION (2011)
LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
Ha Nam Nguyen et al.
CELL STEM CELL (2011)
Specification of neuronal and glial subtypes from human pluripotent stem cells
Huisheng Liu et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis
Arie Neymotin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Astrocytes and Microglia: Responses to Neuropathological Conditions
Sarika Singh et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2011)
New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative Stress
Michael B. Sporn et al.
JOURNAL OF NATURAL PRODUCTS (2011)
Deletion of Astroglial Dicer Causes Non-Cell-Autonomous Neuronal Dysfunction and Degeneration
Jifang Tao et al.
JOURNAL OF NEUROSCIENCE (2011)
Specification of transplantable astroglial subtypes from human pluripotent stem cells
Robert Krencik et al.
NATURE BIOTECHNOLOGY (2011)
A functionally characterized test set of human induced pluripotent stem cells
Gabriella L. Boulting et al.
NATURE BIOTECHNOLOGY (2011)
Constructing and Deconstructing Stem Cell Models of Neurological Disease
Steve S. W. Han et al.
NEURON (2011)
Activation of Nrf2-Regulated Glutathione Pathway Genes by Ischemic Preconditioning
Karen F. S. Bell et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2011)
Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning
Karen F. Bell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state
R. Patani et al.
NATURE COMMUNICATIONS (2011)
Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target gene
Bashayer Mubarak et al.
Channels (2010)
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake
Valentina Diana et al.
EXPERIMENTAL NEUROLOGY (2010)
Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease
Cliona Stack et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
He-Jin Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy
David W. Hampton et al.
JOURNAL OF NEUROSCIENCE (2010)
Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity
Frederic Leveille et al.
JOURNAL OF NEUROSCIENCE (2010)
Amyloid-β Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability
Igor Allaman et al.
JOURNAL OF NEUROSCIENCE (2010)
A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
Alexandria Lau et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Human Embryonic Stem Cell-Derived Neurons as a Tool for Studying Neuroprotection and Neurodegeneration
Giles E. Hardingham et al.
MOLECULAR NEUROBIOLOGY (2010)
Astrocytes Control Breathing Through pH-Dependent Release of ATP
Alexander V. Gourine et al.
SCIENCE (2010)
Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice
Xing-Long Gu et al.
MOLECULAR BRAIN (2010)
RNA oxidation in Alzheimer disease and related neurodegenerative disorders
Akihiko Nunomura et al.
ACTA NEUROPATHOLOGICA (2009)
Gene Expression Profiling of Human Neural Progenitor Cells Following the Serum-Induced Astrocyte Differentiation
Shinya Obayashi et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2009)
The Nrf2-ARE cytoprotective pathway in astrocytes
Marcelo R. Vargas et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)
Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions
Chong Wee Liew et al.
FEBS LETTERS (2009)
Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease
Yifeng Du et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
Hristelina Ilieva et al.
JOURNAL OF CELL BIOLOGY (2009)
Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease
Magali Dumont et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Degeneration in Different Parkinsonian Syndromes Relates to Astrocyte Type and Astrocyte Protein Expression
Yun Ju C. Song et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Uniquely Hominid Features of Adult Human Astrocytes
Nancy Ann Oberheim et al.
JOURNAL OF NEUROSCIENCE (2009)
Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin
Francesc X. Soriano et al.
MOLECULES AND CELLS (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Variation in the safety of induced pluripotent stem cell lines
Kyoko Miura et al.
NATURE BIOTECHNOLOGY (2009)
Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss
Michael M. Halassa et al.
NEURON (2009)
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription
Lichuan Yang et al.
PLOS ONE (2009)
Activin/Nodal Inhibition Alone Accelerates Highly Efficient Neural Conversion from Human Embryonic Stem Cells and Imposes a Caudal Positional Identity
Rickie Patani et al.
PLOS ONE (2009)
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
Pei-Chun Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration
Philipp Koch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
Disease-specific induced pluripotent stem cells
In-Hyun Park et al.
CELL (2008)
Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
Maria C. N. Marchetto et al.
CELL STEM CELL (2008)
Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
Francesco Paolo Di Giorgio et al.
CELL STEM CELL (2008)
Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm
Joseph R. Smith et al.
DEVELOPMENTAL BIOLOGY (2008)
Nucleic acid oxidation in Alzheimer disease
Paula I. Morelra et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Tau Isoform Regulation Is Region- and Cell-Specific in Mouse Brain
Pamela McMillan et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2008)
Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione
Francesc X. Soriano et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1
Takumi Satoh et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Opposite Effects of Zinc on Human and Rat P2X2 Receptors
Rachel K. Tittle et al.
JOURNAL OF NEUROSCIENCE (2008)
Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis
Marcelo R. Vargas et al.
JOURNAL OF NEUROSCIENCE (2008)
Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders
Jacques De Keyser et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
Yirui Sun et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
Angelo C. Lepore et al.
NATURE NEUROSCIENCE (2008)
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
Koji Yamanaka et al.
NATURE NEUROSCIENCE (2008)
Species-specific transcription in mice carrying human chromosome 21
Michael D. Wilson et al.
SCIENCE (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Transplanted Astrocytes internalize deposited β-amyloid peptides in a transgenic mouse model of Alzheimer's disease
Rea Pihlaja et al.
GLIA (2008)
Species-specific pharmacology of trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists
Lana Klionsky et al.
MOLECULAR PAIN (2007)
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
Christian S. Lobsiger et al.
NATURE NEUROSCIENCE (2007)
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons
Hyojin Lee et al.
STEM CELLS (2007)
Tissue-specific transcriptional regulation has diverged significantly between human and mouse
Duncan T. Odom et al.
NATURE GENETICS (2007)
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
Makiko Nagai et al.
NATURE NEUROSCIENCE (2007)
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
Francesco Paolo Di Giorgio et al.
NATURE NEUROSCIENCE (2007)
Ca2+ signals and neuronal death in brain ischemia
Daniele Bano et al.
STROKE (2007)
A scaleable and defined system for generating neural stem cells from human embryonic stem cells
Alexis J. Joannides et al.
STEM CELLS (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
An in vitro model of human dopaminergic neurons derived from embryonic stem cells:: MPP+ toxicity and GDNF neuroprotection
Xianmin Zeng et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
Neeta S. Roy et al.
NATURE MEDICINE (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Astrocytic purinergic signaling coordinates synaptic networks
O Pascual et al.
SCIENCE (2005)
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
GP Fan et al.
DEVELOPMENT (2005)
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling
K Liby et al.
CANCER RESEARCH (2005)
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
KS Christopherson et al.
CELL (2005)
Identification of species-specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1
E Phillips et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation
MR Song et al.
NATURE NEUROSCIENCE (2004)
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
AD Kraft et al.
JOURNAL OF NEUROSCIENCE (2004)
β-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
AY Abramov et al.
JOURNAL OF NEUROSCIENCE (2004)
Differential generation of oligodendrocytes from human and rodent embryonic spinal cord neural precursors
S Chandran et al.
GLIA (2004)
CD44 expression identifies astrocyte-restricted precursor cells
Y Liu et al.
DEVELOPMENTAL BIOLOGY (2004)
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
M Koistinaho et al.
NATURE MEDICINE (2004)
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
AM Clement et al.
SCIENCE (2003)
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
M McMahon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
RG Nagele et al.
BRAIN RESEARCH (2003)
Adult mouse astrocytes degrade amyloid-β in vitro and in situ
T Wyss-Coray et al.
NATURE MEDICINE (2003)
Species-specific differences in the usage of several caspase substrates
S Ussat et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation
WH Ge et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Evolution of transcription factor binding sites in mammalian gene regulatory regions: Conservation and turnover
ET Dermitzakis et al.
MOLECULAR BIOLOGY AND EVOLUTION (2002)
In vitro differentiation of transplantable neural precursors from human embryonic stem cells
SC Zhang et al.
NATURE BIOTECHNOLOGY (2001)
Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds
K Kataoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Oxidative damage is the earliest event in Alzheimer disease
A Nunomura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
NCX1 Na/Ca exchanger splice variants in pancreatic islet cells
F Van Eylen et al.
JOURNAL OF ENDOCRINOLOGY (2001)